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Prostacyclin Receptor 抗体 (AA 101-200) (Cy5.5)

This anti-Prostacyclin Receptor antibody is a 兔 多克隆 antibody detecting Prostacyclin Receptor in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1408385
发货至: 中国

Quick Overview for Prostacyclin Receptor 抗体 (AA 101-200) (Cy5.5) (ABIN1408385)

抗原

See all Prostacyclin Receptor (PTGIR) 抗体
Prostacyclin Receptor (PTGIR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Prostacyclin Receptor antibody is conjugated to Cy5.5

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 101-200

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Prostaglandin I2 Receptor

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Prostacyclin Receptor (PTGIR)

    别名

    Prostaglandin I2 Receptor

    背景

    Synonyms: IP, PGI receptor, PGI2 receptor, PI2R_HUMAN, PRIPR, Prostacyclin receptor, Prostaglandin I2 receptor, Prostanoid IP receptor, PTGIR.

    Background: Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2?, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G protein-coupled prostanoid receptors, designated EP, FP, IP, TP and DP, respectively. The IP Receptor binds prostacyclin, PGI2, the main pro-stanoid synthesized by vascular tissues.Upon binding to the IP Receptor, prostacyclin activates adenylate cyclase primarily through the Gas protein. The gene encoding the human IP Receptor is located on chromosome 19. It is expressed as a glycosylated and phosphorylated protein, which is abundantly expressed in vascular tissues such as aorta, lung, atrium and ventricle, as well as in kidney, thymus, spleen and neurons.

    途径

    cAMP Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling
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