FEN1 抗体 (AbBy Fluor® 488)
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北京 101111
Quick Overview for FEN1 抗体 (AbBy Fluor® 488) (ABIN1405180)
抗原
See all FEN1 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FEN1
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亚型
- IgG
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anti-Flap Structure-Specific Endonuclease 1 (FEN1) (AA 50-380) antibody
FEN1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC, IF, IP, IHC (p), ICC, PLA 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 4D9 unconjugated Recombinant Antibody
anti-Flap Structure-Specific Endonuclease 1 (FEN1) (AA 1-380) antibodyFEN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) (Internal Region) antibodyFEN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Flap Structure-Specific Endonuclease 1 (FEN1) antibodyFEN1 适用: 人, 小鼠 WB, IP 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FEN1 (Flap Structure-Specific Endonuclease 1 (FEN1))
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别名
- FEN1
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背景
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Synonyms: DNase IV, FEN-1, FEN1, FEN1_HUMAN, Flap endonuclease 1, Flap structure specic endonuclease 1, Flap structure-specic endonuclease 1, hFEN-1, hFEN1,Maturation factor 1, MF1, Rad2.
Background: Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.
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基因ID
- 2237
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途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
抗原
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