MUC1 抗体 (AA 941-1040) (AbBy Fluor® 555)
Quick Overview for MUC1 抗体 (AA 941-1040) (AbBy Fluor® 555) (ABIN1396540)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 941-1040
-
交叉反应
- 人
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human MUC1
-
亚型
- IgG
-
-
anti-Mucin 1 (MUC1) (AA 474-630) antibody
MUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 410-525) antibodyMUC1 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人, 小鼠 IHC, WB, ELISA, FACS, IF, Coat, StM 宿主: 小鼠 Monoclonal MUC1-955 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal MUC1-520 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 适用: 人 IHC, WB, IHC (p) 宿主: 小鼠 Monoclonal 2E3 unconjugated
anti-Mucin 1 (MUC1) (AA 1182-1255) antibodyMUC1 适用: 人 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 66-175) antibodyMUC1 适用: 人 IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3B10B4 unconjugated
anti-Mucin 1 (MUC1) (AA 1098-1255) antibodyMUC1 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 404-655) antibodyMUC1 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 1062-1139) antibodyMUC1 适用: 人, 小鼠, 大鼠 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- FCM 1:20-100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- MUC1 (Mucin 1 (MUC1))
-
别名
- MUC1
-
背景
-
Synonyms: Breast carcinoma associated antigen DF3, Breast carcinoma associated antigen DF3, Breast carcinoma-associated antigen DF3, CA 15 3, CA 15-3, CA15 3, CA15 3 antigen, CA15.3, Cancer antigen 15-3, Carcinoma associated mucin, Carcinoma associated mucin, Carcinoma-associated mucin, CD 227, CD227, CD227, CD227 antigen, DF3 antigen, DF3 antigen, EMA, EMA, Episialin, Episialin, Epithelial membrane antigen, Epithelial membrane antigen, Epithelial mucin tandem repeat sequence, H23 antigen, H23 antigen, H23AG, H23AG, HGNC:7508, KL 6, KL-6, KL6, Krebs von den Lungen-6, MAM 6, MAM6, MUC 1, MUC 1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, MUC1_HUMAN, Mucin 1, Mucin 1 precursor, Mucin 1 transmembrane, Mucin-1 subunit beta, Mucin1, Mucin1, Peanut reactive urinary mucin, Peanut reactive urinary mucin, Peanut-reactive urinary mucin, PEM, PEMT, PEMT, Polymorphic epithelial mucin, Polymorphic epithelial mucin, PUM, PUM, Tumor associated epithelial membrane antigen, Tumor associated epithelial membrane antigen, Tumor associated epithelial mucin, Tumor associated mucin, Tumor associated mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin.
Background: MUC1 is a large cell surface mucin glycoprotein expressed by most glandular and ductal epithelial cells and some hematopoietic cell lineages. It is expressed on most secretory epithelium, including mammary gland and some hematopoietic cells. It is expressed abundantly in lactating mammary glands and overexpressed abundantly in >90 % breast carcinomas and metastases. Transgenic MUC1 has been shown to associate with all four cebB receptors and localize with erbB1 (EGFR) in lactating glands. The MUC1 gene contains seven exons and produces several different alternatively spliced variants. The major expressed form of MUC1 uses all seven exons and is a type 1 transmembrane protein with a large extracellular tandem repeat domain. The tandem repeat domain is highly O glycosylated and alterations in glycosylation have been shown in epithelial cancer cells.
-
基因ID
- 4582
-
途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
-
