IFT57 抗体 (AA 331-429) (FITC)
Quick Overview for IFT57 抗体 (AA 331-429) (FITC) (ABIN1392806)
抗原
See all IFT57 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-429
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human HIPPI
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亚型
- IgG
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anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 170-429) antibody
IFT57 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 1-429) antibodyIFT57 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G8 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyIFT57 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 159-193) antibodyIFT57 适用: 人 WB 宿主: 兔 Polyclonal RB57869 unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (AA 214-312) antibodyIFT57 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Intraflagellar Transport 57 Homolog (IFT57) (Internal Region) antibodyVerified IFT57 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- IFT57 (Intraflagellar Transport 57 Homolog (IFT57))
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别名
- HIPPI
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背景
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Synonyms: Dermal papilla derived protein 8, Dermal papilla-derived protein 8, DERP 8, DERP8, Esrrbl 1, Esrrbl1, ESRRBL1 protein, Estrogen related receptor beta like 1, Estrogen related receptor beta like protein 1, Estrogen-related receptor beta like 1, Estrogen-related receptor beta-like protein 1, FLJ10147, Hip1 Interacting Protein, HIP1 interacting protein HIPPI, Hip1 protein interactor, HIP1-interacting protein, HIPPI, Huntingtin interacting protein 1 interacting protein, Huntingtin interacting protein 1 protein interactor, Huntingtin-interacting protein-1 protein interactor, T 57, t57, T57_HUMAN, Intraflagellar transport 57 homolog Chlamydomonas, Intraflagellar transport 57 homolog, Intraflagellar transport protein 57 homolog, MHS4R2, Vestrogen related receptor beta like 1, Vestrogen-related receptor beta like 1, CDNA FLJ10147 fis clone HEMBA1003369.
Background: Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, which occur later in human life. Huntington?s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum. Polyglutamine expansion reduces the level of association between Hip-1 and Htt, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor). The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, which may contribute to the neuronal cell death observed in individuals diagnosed with Huntington?s disease. The human hippi gene maps to chromosome 3q13.13 and encodes a 429 amino acid protein.
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途径
- Hedgehog Signaling, Positive Regulation of Endopeptidase Activity
抗原
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