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Lamin B2 抗体 (AA 61-160) (AbBy Fluor® 555)

This anti-Lamin B2 antibody is a 兔 多克隆 antibody detecting Lamin B2 in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN1389461
发货至: 中国

Quick Overview for Lamin B2 抗体 (AA 61-160) (AbBy Fluor® 555) (ABIN1389461)

抗原

See all Lamin B2 (LMNB2) 抗体
Lamin B2 (LMNB2)

适用

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小鼠

宿主

  • 58
  • 19

克隆类型

  • 54
  • 23
多克隆

标记

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This Lamin B2 antibody is conjugated to AbBy Fluor® 555

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    • 3
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    • 1
    • 1
    • 1
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    AA 61-160

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Lamin B2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Lamin B2 (LMNB2)

    别名

    Lamin B2

    背景

    Synonyms: Alternative namesLAMB 2, LAMB2, Lamin-B2, LMN 2, LMN B2, LMN2, LMNB 2, LMNB2, LMNB2_HUMAN, MGC2721.

    Background: A unique family of Cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed CED-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.

    基因ID

    84823

    UniProt

    Q03252

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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