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PPARG 抗体 (pSer273)

Name: PPARG 抗体 (pSer273)
SKU: ABIN1387919
Availability: OutOfStock

This anti-PPARG antibody is a 兔多克隆 antibody detecting PPARG in WB, ELISA, ICC, IF (cc), IF (p), IHC (p) 和 IHC (fro). Suitable for 人, 小鼠, 大鼠, 绵羊和豚鼠. This Primary Antibody has been cited in 10+ publications.

Image kindly submitted by Dr. (PPARG 抗体 (pSer273))

Lane 1: mouse lung lysates Lane 2: mouse stomach lysates probed with Anti Phospho-PPAR Gamma (ser273) Polyclonal Antibody, Unconjugated (ABIN734663) at 1:200 in 4 °C. (PPARG 抗体 (pSer273))

SDS

2 images

(10 references)

产品编号 ABIN1387919

发货至: 中国

Quick Overview for PPARG 抗体 (pSer273) (ABIN1387919)

抗原

See all PPARG 抗体

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

适用

人, 小鼠, 大鼠, 绵羊, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This PPARG antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Discover our top product PPARG Primary Antibody

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pSer273

交叉反应

豚鼠, 人, 小鼠, 大鼠, 绵羊

预测反应

Cow,Chicken,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human PPAR Gamma around the phosphorylation site of ser273

亚型

IgG
anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 50-150) antibody
PPARG 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 315-420) antibody
PPARG 适用: 人, 小鼠, 大鼠, 山羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 101-200) antibody
PPARG 适用: 人, 小鼠, 大鼠, Cow, 绵羊 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠, 犬 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 149-273) antibody
PPARG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (pSer112) antibody
PPARG 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibody
PPARG 适用: 人 WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 8D1H8F4 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) antibody
PPARG 适用: 小鼠, 大鼠 IHC 宿主: 小鼠 Monoclonal 6D7B9 unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 1-477) antibody
PPARG 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Peroxisome Proliferator-Activated Receptor gamma (PPARG) (AA 349-488) antibody
PPARG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Liu, Wan, Lang, Si, Zhu, Zhou, Mi: "Dihydromyricetin delays the onset of hyperglycemia and ameliorates insulin resistance without excessive weight gain in Zucker diabetic fatty rats." in: Molecular and cellular endocrinology, Vol. 439, pp. 105-115, (2018) (PubMed).

Liu, Zhou, Lang, Zhou, Mi: "Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARγ in 3T3-L1 cells." in: Journal of cellular and molecular medicine, Vol. 22, Issue 2, pp. 1247-1256, (2017) (PubMed).

Abd Alla, Graemer, Fu, Quitterer: "Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice." in: The Journal of biological chemistry, Vol. 291, Issue 6, pp. 2583-600, (2016) (PubMed).

Agrawal, Chanley, Westbrook, Nie, Kitao, Guess, Benndorf, Hidalgo, Smoyer: "Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome." in: Scientific reports, Vol. 6, pp. 24392, (2016) (PubMed).

Maganti, Tersey, Syed, Nelson, Colvin, Maier, Mirmira: "Peroxisome Proliferator-activated Receptor-γ Activation Augments the β-Cell Unfolded Protein Response and Rescues Early Glycemic Deterioration and β Cell Death in Non-obese Diabetic Mice." in: The Journal of biological chemistry, Vol. 291, Issue 43, pp. 22524-22533, (2016) (PubMed).

Stechschulte, Ge, Hinds, Sanchez, Franceschi, Lecka-Czernik et al.: "Protein Phosphatase PP5 Controls Bone Mass and the Negative Effects of Rosiglitazone on Bone through Reciprocal Regulation of PPARγ (Peroxisome Proliferator-activated Receptor γ) and RUNX2 ..." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24475-24486, (2016) (PubMed).

Liu, Feng, Zhu, Liu, Han, Chen, Wang, Li, Li, Xu, Si: "Identification of a novel selective agonist of PPAR? with no promotion of adipogenesis and less inhibition of osteoblastogenesis." in: Scientific reports, Vol. 5, pp. 9530, (2015) (PubMed).

Kolli, Stechschulte, Dowling, Rahman, Czernik, Lecka-Czernik: "Partial agonist, telmisartan, maintains PPAR? serine 112 phosphorylation, and does not affect osteoblast differentiation and bone mass." in: PLoS ONE, Vol. 9, Issue 5, pp. e96323, (2014) (PubMed).

Pandurangan, Park, Kim: "Aspartame downregulates 3T3-L1 differentiation." in: In vitro cellular & developmental biology. Animal, Vol. 50, Issue 9, pp. 851-7, (2014) (PubMed).

Sarr, Thompson, Zhao, Lee, Regnault: "Low birth weight male guinea pig offspring display increased visceral adiposity in early adulthood." in: PLoS ONE, Vol. 9, Issue 6, pp. e98433, (2014) (PubMed).
抗原

PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))

别名

PPAR Gamma

背景

Synonyms: GLM1, CIMT1, NR1C3, PPARG1, PPARG2, PPARgamma, Peroxisome proliferator-activated receptor gamma, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, PPARG
Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.

基因ID

5468

UniProt

P37231

途径

MAPK Pathway, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation