TFAM 抗体 (AA 155-246)
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- 抗原 See all TFAM 抗体
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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抗原表位
- AA 155-246
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TFAM antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Sheep,Pig,Rabbit,Goat
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human MtTF1
- 亚型
- IgG
- Top Product
- Discover our top product TFAM Primary Antibody
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." in: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).
: "Protective effects of PGC-1α via the mitochondrial pathway in rat brains after intracerebral hemorrhage." in: Brain research, Vol. 1646, pp. 34-43, (2016) (PubMed).
: "Acute nitrogen dioxide inhalation induces mitochondrial dysfunction in rat brain." in: Environmental research, Vol. 138, pp. 416-24, (2015) (PubMed).
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Deferoxamine ameliorates adipocyte dysfunction by modulating iron metabolism in ob/ob mice." in: Endocrine connections, Vol. 7, Issue 4, pp. 604-616, (2018) (PubMed).
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- 抗原
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- 别名
- MtTF1 (TFAM 产品)
- 别名
- tcf6 antibody, mttf1 antibody, mttfa antibody, tcf6l1 antibody, tcf6l2 antibody, tcf6l3 antibody, mttfa-A antibody, xl-mtTFA antibody, MGC153358 antibody, zgc:153358 antibody, MTTF1 antibody, MTTFA antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, AI661103 antibody, Hmgts antibody, mtTFA antibody, tsHMG antibody, Mttfa antibody, transcription factor A, mitochondrial antibody, transcription factor A, mitochondrial L homeolog antibody, TFAM antibody, tfam.L antibody, tfam antibody, Tfam antibody
- 背景
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Synonyms: TCF6, MTTF1, MTTFA, TCF6L1, TCF6L2, TCF6L3, Transcription factor A, mitochondrial, Mitochondrial transcription factor 1, Transcription factor 6, TCF-6, Transcription factor 6-like 2, TFAM
Background: Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
- 基因ID
- 7019
- UniProt
- Q00059
- 途径
- Chromatin Binding
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