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Hexokinase 2 抗体

HK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN1387310
发货至: 中国
  • 抗原 See all Hexokinase 2 (HK2) 抗体
    Hexokinase 2 (HK2)
    适用
    • 80
    • 29
    • 23
    • 5
    • 5
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    • 3
    • 3
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    • 1
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    人, 小鼠, 大鼠
    宿主
    • 69
    • 20
    克隆类型
    • 69
    • 20
    多克隆
    标记
    • 54
    • 8
    • 8
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    • 1
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    This Hexokinase 2 antibody is un-conjugated
    应用范围
    • 72
    • 38
    • 38
    • 12
    • 12
    • 12
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Hexokinase II/HxK2
    亚型
    IgG
    Top Product
    Discover our top product HK2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    有效期
    12 months
  • 抗原
    Hexokinase 2 (HK2)
    别名
    Hexokinase 2 (HK2 产品)
    别名
    HKII antibody, HXK2 antibody, AI642394 antibody, hexokinase-2 antibody, fi09d05 antibody, fi17h06 antibody, wu:fi09d05 antibody, wu:fi17h06 antibody, wu:fi31b04 antibody, zgc:55926 antibody, HK2 antibody, ARABIDOPSIS THALIANA HEXOKINASE 2 antibody, ATHXK2 antibody, F6F22.11 antibody, F6F22_11 antibody, HEXOKINASE 2 antibody, hexokinase 2 antibody, StHK2 antibody, hexokinase 2 antibody, hexokinase-2 antibody, hexokinase 2 L homeolog antibody, HK2 antibody, Hk2 antibody, hk2 antibody, HXK2 antibody, LOC100032849 antibody, hk2.L antibody, hxk2 antibody, LOC102577690 antibody
    背景

    Synonyms: Hexokinase 2, Hexokinase 2 muscle, Hexokinase type II, Hexokinase-2, HK 2, HK II, HK2, HKII, HxK 2, HxK2, HXK2_HUMAN, Muscle form hexokinase.

    Background: The hexokinases utilize Mg-ATP as a phosphoryl donor to catalyze the first step of intracellular glucose metabolism, the conversion of glucose to glucose-6-phosphate. Four hexokinase isoenzymes have been identified, including hexokinase I (HXK I), hexokinase II (HXK II), hexokinase III (HXK III) and hexokinase IV (HXK IV, also designated glucokinase or GCK). Hexokinases I-III each contain an N-terminal cluster of hydrophobic amino acids. Glucokinase lacks the N-terminal hydrophobic cluster. The hydrophobic cluster is thought to be necessary for membrane binding. This is substantiated by the finding that glucokinase has lower affinity for glucose than do the other hexokinases. HXK I has been shown to be expressed in brain, kidney and heart tissues as well as in hepatoma cell lines. HXK II is involved in the uptake and utilization of glucose by adipose and skeletal tissues. Of the hexokinases, HXK III has the highest affinity for glucose. Glucokinase is expressed in pancreatic beta cells where it functions as a glucose sensor, determining the set point? for insulin secretion.

    基因ID
    3099
    途径
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
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