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Hexokinase 2 抗体 (AA 401-431)

HK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB03920 unconjugated
产品编号 ABIN392756
发货至: 中国
  • 抗原 See all Hexokinase 2 (HK2) 抗体
    Hexokinase 2 (HK2)
    抗原表位
    • 16
    • 9
    • 8
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 401-431
    适用
    • 80
    • 30
    • 24
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    宿主
    • 69
    • 20
    克隆类型
    • 69
    • 20
    多克隆
    标记
    • 54
    • 8
    • 8
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Hexokinase 2 antibody is un-conjugated
    应用范围
    • 72
    • 38
    • 38
    • 12
    • 12
    • 12
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    纯化方法
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    免疫原
    This HK2 (Hexokinase II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 401-431 amino acids from the Central region of human HK2 (Hexokinase II).
    克隆位点
    RB03920
    亚型
    Ig Fraction
    Top Product
    Discover our top product HK2 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • 抗原
    Hexokinase 2 (HK2)
    别名
    HK2 (Hexokinase II) (HK2 产品)
    别名
    HKII antibody, HXK2 antibody, AI642394 antibody, hexokinase-2 antibody, fi09d05 antibody, fi17h06 antibody, wu:fi09d05 antibody, wu:fi17h06 antibody, wu:fi31b04 antibody, zgc:55926 antibody, HK2 antibody, ARABIDOPSIS THALIANA HEXOKINASE 2 antibody, ATHXK2 antibody, F6F22.11 antibody, F6F22_11 antibody, HEXOKINASE 2 antibody, hexokinase 2 antibody, StHK2 antibody, hexokinase 2 antibody, hexokinase-2 antibody, hexokinase 2 L homeolog antibody, HK2 antibody, Hk2 antibody, hk2 antibody, HXK2 antibody, LOC100032849 antibody, hk2.L antibody, hxk2 antibody, LOC102577690 antibody
    背景
    In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus. Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
    分子量
    102380
    基因ID
    3099
    NCBI登录号
    NP_000180
    UniProt
    P52789
    途径
    PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
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