Hexokinase 2 抗体 (N-Term)
(1 reference)-
- 抗原 See all Hexokinase 2 (HK2) 抗体
- Hexokinase 2 (HK2)
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抗原表位
- AA 91-121, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Hexokinase 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M, Pig, Rat
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This HK2 (Hexokinase II) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-121 amino acids from the N-terminal region of human HK2 (Hexokinase II).
- 克隆位点
- RB3917
- 亚型
- Ig Fraction
- Top Product
- Discover our top product HK2 Primary Antibody
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anti-Hexokinase 2 (HK2) (AA 1-120) antibody
HK2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 818-917) antibodyHK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4H1 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 3D3 unconjugated
anti-Hexokinase 2 (HK2) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (C-Term) antibodyHK2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 469-669) antibodyHK2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hexokinase 2 (HK2) (AA 453-483) antibodyHK2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5333 unconjugated
anti-Hexokinase 2 (HK2) (AA 334-526) antibodyHK2 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1438-45, (2009) (PubMed).
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: "Analyses of resected human brain metastases of breast cancer reveal the association between up-regulation of hexokinase 2 and poor prognosis." in: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1438-45, (2009) (PubMed).
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- 抗原
- Hexokinase 2 (HK2)
- 别名
- HK2 (Hexokinase II) (HK2 产品)
- 别名
- HKII antibody, HXK2 antibody, AI642394 antibody, hexokinase-2 antibody, fi09d05 antibody, fi17h06 antibody, wu:fi09d05 antibody, wu:fi17h06 antibody, wu:fi31b04 antibody, zgc:55926 antibody, HK2 antibody, ARABIDOPSIS THALIANA HEXOKINASE 2 antibody, ATHXK2 antibody, F6F22.11 antibody, F6F22_11 antibody, HEXOKINASE 2 antibody, hexokinase 2 antibody, StHK2 antibody, hexokinase 2 antibody, hexokinase-2 antibody, hexokinase 2 L homeolog antibody, HK2 antibody, Hk2 antibody, hk2 antibody, HXK2 antibody, LOC100032849 antibody, hk2.L antibody, hxk2 antibody, LOC102577690 antibody
- 背景
- In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase activity is involved in the first step in several metabolic pathways. HK3 is bound to the outer mitochondrial membrane. Its hydrophobic N-terminal sequence may be involved in membrane bindng. It is the predominant hexokinase isozyme expressed in insuline-responsive tissues such as skeletal muscle. The N- and C-terminal halves of this hexokinase show extensive sequence similarity to each other. The catalytic activity is associated with the C-terminus while regulatory function is associated wiht the N-terminus. Although found in NIDDM patients, genetic variations of HK2 do not contribute to the disease.
- 分子量
- 102380
- 基因ID
- 3099
- NCBI登录号
- NP_000180
- UniProt
- P52789
- 途径
- PI3K-Akt Signaling, Carbohydrate Homeostasis, Warburg Effect
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