SOX10 抗体
Quick Overview for SOX10 抗体 (ABIN1386776)
抗原
See all SOX10 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SOX10
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亚型
- IgG
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anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibody
SOX10 适用: 人, 小鼠 WB, IHC, StM 宿主: 小鼠 Monoclonal SOX10-991 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (Middle Region) antibodySOX10 适用: 人, 小鼠, 大鼠, Cow, 犬, 兔, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 147-252) antibodySOX10 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 2E7E8 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 147-252) antibodySOX10 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2E7B5 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 231-259) antibodySOX10 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21835 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibodySOX10 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal SOX10-992 unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibodySOX10 适用: 人, 小鼠 IHC, StM 宿主: 兔 Monoclonal SOX10-2311R unconjugated Recombinant Antibody
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 115-269) antibodySOX10 适用: 人, 小鼠 IHC, StM 宿主: 小鼠 Monoclonal rSOX10-1074 unconjugated Recombinant Antibody
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 200-300) antibodySOX10 适用: 人 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) (AA 231-259) antibodySOX10 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1:100-1000, IHC-P: 1:100-500, IF(IHC-P): 1:50-200
Optimal working dilution should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- SOX10 (SRY (Sex Determining Region Y)-Box 10 (SOX10))
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别名
- Sox10
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背景
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Synonyms: DOM, MGC15649, SOX 10, SOX10, SOX10_HUMAN, SRY sex determining region Y box 10, SRY box containing gene 10, SRY related HMG box gene 10, Transcription factor SOX 10, Transcription factor SOX-10, WS4.
Background: Transcription factor that seems to function synergistically with the POU domain protein TST-1/OCT6/SCIP. Could confer cell specificity to the function of other transcription factors in developing and mature glia. Involvement in disease, Defects in SOX10 are the cause of Waardenburg syndrome type 2E (WS2E) . WS2 is a genetically heterogeneous, autosomal dominant disorder characterized by sensorineural deafness, pigmentary disturbances, and absence of dystopia canthorum. The frequency of deafness is higher in WS2 than in WS1.Defects in SOX10 are a cause of Waardenburg syndrome type 4C (WS4C), also known as Waardenburg-Shah syndrome. WS4C is characterized by the association of Waardenburg features (depigmentation and deafness) and the absence of enteric ganglia in the distal part of the intestine (Hirschsprung disease).Defects in SOX10 are a cause of Yemenite deaf-blind hypopigmentation syndrome (YDBHS) . YDBHS consists of cutaneous hypopigmented and hyperpigmented spots and patches, microcornea, coloboma and severe hearing loss. Another case observed in a girl with similar skin symptoms and hearing loss but without microcornea or coloboma is reported as a mild form of this syndrome.
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基因ID
- 6663
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途径
- Chromatin Binding
抗原
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