P2RX7 抗体 (AA 115-160)
Quick Overview for P2RX7 抗体 (AA 115-160) (ABIN1386314)
抗原
See all P2RX7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 115-160
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human P2RX7
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." in: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol. 57, pp. 138-144, (2017) (PubMed).
: "P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation." in: International journal of molecular medicine, Vol. 35, Issue 5, pp. 1179-88, (2015) (PubMed).
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: "P2X7 receptor in spinal tuberculosis: Gene polymorphisms and protein levels in Chinese Han population." in: Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases, Vol. 57, pp. 138-144, (2017) (PubMed).
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- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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别名
- P2RX7
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背景
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Synonyms: P2X7, P2X purinoceptor 7, ATP receptor, P2Z receptor, Purinergic receptor, P2RX7
Background: Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells.
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基因ID
- 5027
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UniProt
- Q99572
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
抗原
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