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p300 抗体 (AA 1451-1600)

This anti-p300 antibody is a 兔 多克隆 antibody detecting p300 in WB, ELISA, IHC (p), ICC, IF (cc), IF (p) 和 IHC (fro). Suitable for 人 和 小鼠.
产品编号 ABIN1386187
发货至: 中国

Quick Overview for p300 抗体 (AA 1451-1600) (ABIN1386187)

抗原

See all p300 (EP300) 抗体
p300 (EP300) (E1A Binding Protein P300 (EP300))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This p300 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 1451-1600

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human EP300 inhibitory protein 1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    p300 (EP300) (E1A Binding Protein P300 (EP300))

    别名

    Ep300

    背景

    Synonyms: CREBBP/EP300 inhibitory protein 1, Cyclic AMP responsive enhancer binding protein, E1A associated protein p300, E1A binding protein p300, E1A-associated protein p300, EC 2.3.1.48, EP300, EP300: E1A binding protein p300, EP300_HUMAN, istone acetyltransferase p300, 300 HAT, RB and P300 binding protein EID 1, Retinoblastoma protein associated protein, RSTS2.

    Background: Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 Molecules lacking an intact E1A binding site bypass E1A repression even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators.

    途径

    p53 Pathway, Notch Signaling, Interferon-gamma Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha, Regulation of Muscle Cell Differentiation, Regulation of Cell Size
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