NFATC4 抗体 (AA 480-530)
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北京 101111
Quick Overview for NFATC4 抗体 (AA 480-530) (ABIN1386186)
抗原
See all NFATC4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 480-530
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human NF-ATc4
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).
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: "Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).
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- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
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别名
- NF-ATc4
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背景
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Synonyms: NFAT3, NF-AT3, NF-ATC4, Nuclear factor of activated T-cells, cytoplasmic 4, NFATc4, T-cell transcription factor NFAT3
Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors, this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
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基因ID
- 4776
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UniProt
- Q14934
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途径
- RTK signaling, WNT signaling
抗原
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