NFATC4 抗体 (AA 480-530)
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- 抗原 See all NFATC4 抗体
- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
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抗原表位
- AA 480-530
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NFATC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human NF-ATc4
- 亚型
- IgG
- Top Product
- Discover our top product NFATC4 Primary Antibody
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).
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Chronic intermittent hypoxia induces cardiac hypertrophy by impairing autophagy through the adenosine 5'-monophosphate-activated protein kinase pathway." in: Archives of biochemistry and biophysics, Vol. 606, pp. 41-52, (2016) (PubMed).
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- 抗原
- NFATC4 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 4 (NFATC4))
- 别名
- NF-ATc4 (NFATC4 产品)
- 别名
- si:dkeyp-66d1.4 antibody, NFATC4 antibody, 3110041H08Rik antibody, AW107667 antibody, AW546455 antibody, Nfat3 antibody, NF-ATc4 antibody, NFAT3 antibody, nuclear factor of activated T-cells 4 antibody, nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 antibody, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 antibody, NFATC4 antibody, nfatc4 antibody, Nfatc4 antibody
- 背景
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Synonyms: NFAT3, NF-AT3, NF-ATC4, Nuclear factor of activated T-cells, cytoplasmic 4, NFATc4, T-cell transcription factor NFAT3
Background: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors, this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation. May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.
- 基因ID
- 4776
- UniProt
- Q14934
- 途径
- RTK signaling, WNT signaling
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