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HEXIM1 抗体

This anti-HEXIM1 antibody is a 兔 多克隆 antibody detecting HEXIM1 in WB, IHC (p) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1386067
发货至: 中国

Quick Overview for HEXIM1 抗体 (ABIN1386067)

抗原

See all HEXIM1 抗体
HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HEXIM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HEXIM1/EDG1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    HEXIM1 (Hexamethylene Bis-Acetamide Inducible 1 (HEXIM1))

    别名

    HEXIM1

    背景

    Synonyms: Cardiac lineage protein 1, CLP 1, CLP1, EDG 1, EDG1, Estrogen down-regulated gene 1 protein, Hexamethylene bis acetamide inducible 1, Hexamethylene bis acetamide inducible protein, Hexamethylene bis acetamide inducible transcript 1, Hexamethylene bis-acetamide-inducible protein 1, HEXI1_HUMAN, HEXIM 1, Hexim1, HEXIM1 protein, HIS 1, HIS1, HMBA inducible, MAQ 1, MAQ1, Menage a quatre 1, Menage a quatre protein 1, Protein HEXIM1.

    Background: Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive transcription elongation factor b (P-TEFb) through association with 7SK. P-TEFb is composed of a catalytic subunit, Cdk9, and either Cyclin T1 or T2 as a regulatory subunit. This complex regulates eukaryotic gene expression at the level of elongation. The C-terminal domains of HEXIM proteins interact directly with each other. Via these domains, HEXIM1 and HEXIM2 form stable homo- and hetero-oligomers, which may aid in the formation of the 7SK small nuclear ribonucleic acid particle. Despite their similar functions, HEXIM1 and HEXIM2 exhibit distinct expression patterns in various established cell lines and human tissues.

    基因ID

    10614
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