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TPD52L1 抗体

This anti-TPD52L1 antibody is a 兔 多克隆 antibody detecting TPD52L1 in WB, IF (p) 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1385481
发货至: 中国

Quick Overview for TPD52L1 抗体 (ABIN1385481)

抗原

See all TPD52L1 抗体
TPD52L1 (Tumor Protein D52-Like 1 (TPD52L1))

适用

人, 小鼠, 大鼠

宿主

  • 22
  • 4
  • 1

克隆类型

  • 25
  • 2
多克隆

标记

  • 15
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TPD52L1 antibody is un-conjugated

应用范围

  • 19
  • 15
  • 6
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human TPD52L1/D53

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    TPD52L1 (Tumor Protein D52-Like 1 (TPD52L1))

    别名

    D53

    背景

    Synonyms: D53, D54, hD53, hD54, Tpd52l1, TPD52L2 TPD53_HUMAN, Tumor protein D52 like 1, Tumor protein D52 like 2, Tumor protein D52-like 1, Tumor protein D53, Tumor protein D54.

    Background: The cell commits to dividing during the G2/M phase transition, and the timing of mitotic entry is tightly regulated to guarantee correct chromosome segregation. D53, also referred to as tumor protein D52-like 1 (TPD52L1), is a coiled-coil motif-bearing member of the D52 tumor protein family. D53 intereacts with 14-3-3, a negative regulator of the G2/M transition, in breast cancer cells. Expression of D53 is highly upregulated at the G2/M phase transition in breast cancer cell lines, and deregulated expression of this protein can adversely affect the completion of mitosis. D53 may function as a signaling intermediate and/or regulator of vesicle trafficking and cell proliferation.

    基因ID

    7164

    途径

    Positive Regulation of Endopeptidase Activity
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