NCF1 抗体 (pSer359)
(1 reference)Quick Overview for NCF1 抗体 (pSer359) (ABIN1385194)
抗原
See all NCF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer359
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交叉反应
- 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human NCF1 around the phosphorylation site of Ser359
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亚型
- IgG
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anti-Neutrophil Cytosol Factor 1 (NCF1) (C-Term) antibody
Verified NCF1 适用: 人, 小鼠, Pig WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (AA 151-250) antibodyNCF1 适用: 人, 小鼠, 马 WB, ELISA, IHC (p), IF (cc), FACS 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (AA 63-232) antibodyNCF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (Ser304) antibodyNCF1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (C-Term) antibodyNCF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (pSer359) antibodyNCF1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (AA 1-390) antibodyNCF1 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) antibodyNCF1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) antibodyNCF1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosol Factor 1 (NCF1) (AA 331-380), (pSer359) antibodyNCF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "Limb Remote Ischemic Postconditioning Reduces Ischemia-Reperfusion Injury by Inhibiting NADPH Oxidase Activation and MyD88-TRAF6-P38MAP-Kinase Pathway of Neutrophils." in: International journal of molecular sciences, Vol. 17, Issue 12, (2016) (PubMed).
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: "Limb Remote Ischemic Postconditioning Reduces Ischemia-Reperfusion Injury by Inhibiting NADPH Oxidase Activation and MyD88-TRAF6-P38MAP-Kinase Pathway of Neutrophils." in: International journal of molecular sciences, Vol. 17, Issue 12, (2016) (PubMed).
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- NCF1 (Neutrophil Cytosol Factor 1 (NCF1))
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别名
- NCF1/p47 phox
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背景
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Synonyms: NCF1Ser359, p47 phoxSer359, NCF1 phospho S359, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, NADPH oxidase organizer 2, NCF 47K, Neutrophil cytosol factor 1, Neutrophil cytosolic factor 1, Neutrophil NADPH oxidase factor 1, Nox organizer 2, Nox organizing protein 2, NOXO2, p47 phox, p47phox, ,SH3 and PX domain containing protein 1A, SH3PXD1A, NADPH oxidase p47 phox, NCF1_HUMAN.
Background: The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47-phox and p67-phox. The cytosolic proteins p47-phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47-phox and p67-phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47-phox, suggesting that p47-phox may faciliate the transport of p67-phox to the membrane.
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基因ID
- 653361
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途径
- PI3K-Akt Signaling
抗原
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