Collagen Type I 抗体
Quick Overview for Collagen Type I 抗体 (ABIN1385105)
抗原
See all Collagen Type I (COL1) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- Cow, 犬, 人, 小鼠, Pig, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Collagen alpha-1(I) chain
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亚型
- IgG
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应用备注
- WB (1:100-500),IHC-P (1:100-500),IF (p) (1:100-500)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- Collagen Type I (COL1) (Collagen, Type I (COL1))
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别名
- Collagen I
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背景
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Synonyms: Collagen type I, Alpha 1 type I collagen, Alpha 2 type I collagen, COL1A1, COL1A2, Collagen I alpha 1 polypeptide, Collagen I alpha 2 polypeptide, Collagen Of Skin Tendon And Bone, Collagen Type 1, Collagen type I alpha 1, Collagen type I alpha 2, OI4, Osteogenesis Imperfecta Type IV, Pro alpha 1I collagen, Type I procollagen, CO1A1_HUMAN.
Background: Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
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分子量
- 161kDa
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基因ID
- 1277
抗原
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