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Collagen Type I 抗体

Name: Collagen Type I 抗体
Brand: antibodies-online
SKU: ABIN135046
Availability: OutOfStock

COL1 适用: 人 ELISA 宿主: 山羊 Polyclonal unconjugated

Decreases in the levels of activated HSC markers, SOX9, COL1 and phosphoMyl9 (PMYL9) following PAK-1 abrogation by siRNA1 in activated rat HSCs relative to their respective scrambled control levels.

Characterisation of COL1 expression in control and Sox9-null animals following liver fibrosis induction using ABIN135046.

IHC

Activated mouse HSCs (‘Control') show decreased protein levels for α-SMA, COL1 and SOX9 by immunoblotting following the loss of integrin beta-1 (‘Itgb1-null').

Elevated collagen levels in skeletal muscles in SGCA- and SGCD-null mice and in the heart of SGCD-null mice investigated using ABIN135046: Immunofluorescent images of skeletal muscles stained with collagen type I (fibrotic marker, green) and laminin (extracellular matrix of muscle fibres, red) Scale bar: 100 μm.

Immunofluorescence images of the heart stained with collagen type I (fibrotic marker, green) using ABIN135046.

(A) Effects on collagen deposition in indirect (inserts) and direct coculture of human dermal fibroblasts and siRNA-treated THP1 cells.

Immunoblot analysis of primary AF and NP cell lysates from two independent donors, D1 (P0) and D3 (P1), respectively, for COL1A1 (ABIN135046) and COL2A1 (ABIN135048).

8 images

(69 references)

产品编号 ABIN135046

发货至: 中国

Datasheet as PDF

抗原 See all Collagen Type I (COL1) 抗体

Collagen Type I (COL1) (Collagen, Type I (COL1))
适用
95

63

60

20

18

17

15

6

5

3

2

2

2

2

2

2

1
人
宿主
69

35

13
山羊
Compatible Secondaries
克隆类型
82

35
多克隆
标记
58

14

7

6

3

3

3

3

3

3

3

3

3

2

2

1
This Collagen Type I antibody is un-conjugated
应用范围
71

46

38

36

33

28

27

25

20

18

17

9

6

6

5

4

1

1
ELISA

特异性

Reacts with conformational determinants on type I collagen Referenced species reactivities include - Human 1-5,10,20,26,27,29,31-34 Chicken 17 Hamster 11,18 Mouse 24,27,28 Chinchilla 19 Porcine 5,21 Rat 5,13-15,23,25,27,35 Elephant 8 Rabbit 16,30 Bovine 6,20 Feline 9 Sheep 7 Canine 5,12 Guinea Pig 16 Tree Shrew 22

交叉反应（详细）

Exhibits < 10 % cross reactivity with collagen type II, III, IV, V and VI. The antibody has not been tested for reactivity with other ECM proteins (e.g., laminin, fibronectin).

产品特性

Goat Anti-Type I Collagen-UNLB

纯化方法

Purification Method: Affinity chromatography on type I collagen covalently linked to agarose.

亚型

IgG

Top Product

Discover our top product COL1 Primary Antibody
anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I (COL1) (AA 1321-1400) antibody
COL1 适用: 人, 大鼠, 小鼠, 兔, 犬, 鱼 WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc), FACS 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I (COL1) (AA 1051-1150) antibody
COL1 适用: 人, 大鼠, 小鼠, 兔 WB, ELISA, IHC (fro), IHC (p), IF (p), IF (cc), ICC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Collagen, Type I (COL1) antibody (FITC)
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, IHC, IP, FACS 宿主: 兔 Polyclonal FITC

anti-Collagen, Type I (COL1) antibody (Biotin)
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, ELISA, IHC, IP, FACS 宿主: 兔 Polyclonal Biotin

anti-Collagen, Type I (COL1) antibody (HRP)
COL1 适用: 人, 大鼠, 小鼠, Cow, 哺乳动物 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal HRP

anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal 3G3 unconjugated

anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 大鼠, 小鼠 IHC (p), IF 宿主: 小鼠 Monoclonal 4H10 unconjugated

anti-Collagen, Type I (COL1) antibody (Biotin)
COL1 适用: 人 ELISA 宿主: 山羊 Polyclonal Biotin

anti-Collagen, Type I (COL1) antibody
COL1 适用: 人, 小鼠, 哺乳动物, 鱼, Amphibian, Avian WB, IHC (fro), IHC (p), IF 宿主: 兔 Polyclonal unconjugated

应用备注
- Applications: Quality tested applications include - ELISA , FLISA
- Other referenced applications include - IHC-PS , IHC-FS , ICC , EM , FC , WB , IP
- Working Dilutions: ELISA BIOT conjugate 1:1,000 - 1:4,000 FLISA FITC and AF488 conjugates 1:200 - 1:400
样本量

0,5 mL

限制

仅限研究用
浓度

0.4 mg/mL

缓冲液

0.2 mg of purified immunoglobulin in 0.5 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

储存液

Without preservative

注意事项

Each reagent is stable for the period shown on the bottle label if stored as directed.

储存条件

4 °C

储存方法

Store at 2-8°C
Corciulo, Castro, Coughlin, Jacob, Li, Fenyö, Rifkin, Kennedy, Cronstein: "Intraarticular injection of liposomal adenosine reduces cartilage damage in established murine and rat models of osteoarthritis." in: Scientific reports, Vol. 10, Issue 1, pp. 13477, (2020) (PubMed).

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抗原

Collagen Type I (COL1) (Collagen, Type I (COL1))

别名

Type I Collagen (COL1 产品)

别名

collagen type III alpha 1 chain antibody, COL3A1 antibody