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Collagen Type I 抗体

The 小鼠 单克隆 anti-Collagen Type I antibody (Clone 4H10) (ABIN7212386) specifically detects Collagen Type I in IHC 和 IF. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7212386
发货至: 中国
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Quick Overview for Collagen Type I 抗体 (ABIN7212386)

抗原

See all Collagen Type I (COL1) 抗体
Collagen Type I (COL1) (Collagen, Type I (COL1))

适用

  • 98
  • 51
  • 45
  • 17
  • 15
  • 5
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  • 3
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  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 65
  • 38
  • 13
小鼠

克隆类型

  • 69
  • 47
单克隆

标记

  • 61
  • 14
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Collagen Type I antibody is un-conjugated

应用范围

  • 75
  • 43
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  • 13
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  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF)

克隆位点

4H10
  • 原理

    Mouse Anti-Collagen I Mouse Monoclonal Antibody (4H10)

    特异性

    The antibody detects endogenous Collagen I protein.

    纯化方法

    The antibody was affinity-purified from mouse antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    Synthetic Peptide of Collagen I

    亚型

    IgG1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:50-200,IHC 1:50-300

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Collagen Type I (COL1) (Collagen, Type I (COL1))

    别名

    Collagen I

    背景

    Collagen alpha-1(I) chain, Alpha-1 type I collagenCOL1A1 (collagen type I alpha 1 chain) encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in COL1A1 are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for COL1A1.

    分子量

    139kD

    基因ID

    1277, 1278

    UniProt

    P02452
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