CD40 抗体
Quick Overview for CD40 抗体 (ABIN1383854)
抗原
See all CD40 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognises the Bp50 antigen, a 48 kDa protein
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纯化方法
- Ion exchange chromatography
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过滤
- 0.22 μm filtered
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免疫原
- Raji cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
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亚型
- IgG1 kappa
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Biological Activity Comment
- Stimulates B-cell proliferation together with IL-4
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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: "Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40." in: Blood, Vol. 106, Issue 8, pp. 2806-14, (2005) (PubMed).
: "In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment." in: Blood, Vol. 102, Issue 12, pp. 4084-9, (2003) (PubMed).
: "Extracellular signal-regulated protein kinase signaling pathway negatively regulates the phenotypic and functional maturation of monocyte-derived human dendritic cells." in: Blood, Vol. 98, Issue 7, pp. 2175-82, (2001) (PubMed).
: "CD86 (B7-2) on human B cells. A functional role in proliferation and selective differentiation into IgE- and IgG4-producing cells." in: The Journal of biological chemistry, Vol. 272, Issue 25, pp. 15613-9, (1997) (PubMed).
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: "Differential effect of agonistic anti-CD40 on human mature and immature dendritic cells: the Janus face of anti-CD40." in: Blood, Vol. 106, Issue 8, pp. 2806-14, (2005) (PubMed).
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