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IL-6 Receptor 抗体

This anti-IL-6 Receptor antibody is a 小鼠 单克隆 antibody detecting IL-6 Receptor in ELISA 和 FACS. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1383676
发货至: 中国

Quick Overview for IL-6 Receptor 抗体 (ABIN1383676)

抗原

See all IL-6 Receptor (IL6R) 抗体
IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

适用

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宿主

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小鼠

克隆类型

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  • 1
单克隆

标记

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This IL-6 Receptor antibody is un-conjugated

应用范围

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ELISA, Flow Cytometry (FACS)

克隆位点

B-N12
  • 特异性

    Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

    纯化方法

    Ion exchange chromatography

    过滤

    0.22 μm filtered

    免疫原

    gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells

    亚型

    IgG1 kappa
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free

    储存液

    Without preservative

    储存条件

    4 °C

    储存方法

    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Labbozzetta, Notarbartolo, Poma, Giannitrapani, Cervello, Montalto, DAlessandro: "Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma." in: Annals of the New York Academy of Sciences, Vol. 1089, pp. 268-75, (2007) (PubMed).

    Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: "STAT3 is constitutively activated in Hodgkin cell lines." in: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).

    Lebeau, Montero Julian, Wijdenes, Müller-Newen, Dahmen, Chérel, Heinrich, Brailly, Hallet, Godard, Minvielle, Jacques: "Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties." in: FEBS letters, Vol. 407, Issue 2, pp. 141-7, (1997) (PubMed).

    Müller-Newen, Köhne, Keul, Hemmann, Müller-Esterl, Wijdenes, Brakenhoff, Hart, Heinrich: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." in: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).

    Mouthon, Freund, Titeux, Katz, Guichard, Breton-Gorius, Vainchenker: "Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis." in: Blood, Vol. 84, Issue 4, pp. 1085-97, (1994) (PubMed).

  • 抗原

    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

    别名

    CD126

    背景

    IL-6R / gp80

    分子量

    80 kDa

    途径

    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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