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IL-6 Receptor 抗体

IL6R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal B-N12 unconjugated
产品编号 ABIN1383676
发货至: 中国
  • 抗原 See all IL-6 Receptor (IL6R) 抗体
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    适用
    • 44
    • 17
    • 16
    宿主
    • 42
    • 23
    • 5
    • 1
    小鼠
    克隆类型
    • 44
    • 26
    • 1
    单克隆
    标记
    • 50
    • 13
    • 5
    • 1
    • 1
    • 1
    This IL-6 Receptor antibody is un-conjugated
    应用范围
    • 52
    • 24
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    • 22
    • 12
    • 10
    • 4
    • 3
    • 3
    • 3
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    ELISA, Flow Cytometry (FACS)
    特异性
    Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein
    纯化方法
    Ion exchange chromatography
    过滤
    0.22 μm filtered
    免疫原
    gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
    克隆位点
    B-N12
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IL6R Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    储存液
    Without preservative
    储存条件
    4 °C
    储存方法
    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Labbozzetta, Notarbartolo, Poma, Giannitrapani, Cervello, Montalto, DAlessandro: "Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma." in: Annals of the New York Academy of Sciences, Vol. 1089, pp. 268-75, (2007) (PubMed).

    Kube, Holtick, Vockerodt, Ahmadi, Haier, Behrmann, Heinrich, Diehl, Tesch: "STAT3 is constitutively activated in Hodgkin cell lines." in: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).

    Lebeau, Montero Julian, Wijdenes, Müller-Newen, Dahmen, Chérel, Heinrich, Brailly, Hallet, Godard, Minvielle, Jacques: "Reconstitution of two isoforms of the human interleukin-11 receptor and comparison of their functional properties." in: FEBS letters, Vol. 407, Issue 2, pp. 141-7, (1997) (PubMed).

    Müller-Newen, Köhne, Keul, Hemmann, Müller-Esterl, Wijdenes, Brakenhoff, Hart, Heinrich: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." in: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).

    Mouthon, Freund, Titeux, Katz, Guichard, Breton-Gorius, Vainchenker: "Growth and differentiation of the human megakaryoblastic cell line (ELF-153): a model for early stages of megakaryocytopoiesis." in: Blood, Vol. 84, Issue 4, pp. 1085-97, (1994) (PubMed).

  • 抗原
    IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
    别名
    CD126 (IL6R 产品)
    背景
    IL-6R / gp80
    分子量
    80 kDa
    途径
    JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
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