IL-6 Receptor 抗体
(9 references)Quick Overview for IL-6 Receptor 抗体 (ABIN1383672)
抗原
See all IL-6 Receptor (IL6R) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognises the Interleukin-6 Ra subunit, IL-6 Ra, IL-6 R, a 80 kDa protein
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纯化方法
- Ion exchange chromatography
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过滤
- 0.22 μm filtered
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免疫原
- gp80 transfected CHO cell line,Myeloma X63/AG.8653 x Balb/c spleen cells
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亚型
- IgG1 kappa
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Biological Activity Comment
- Inhibits IL-6 induced proliferation of XG-1 cells
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anti-Interleukin 6 Receptor (IL6R) antibody
IL6R 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 20-320) antibodyIL6R 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 216-356) antibodyIL6R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) antibodyIL6R 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 205-347) antibodyIL6R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 385-462) antibodyIL6R 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 1-468) antibodyIL6R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 21-120) antibodyIL6R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G6 unconjugated
anti-Interleukin 6 Receptor (IL6R) (AA 21-120) antibodyIL6R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E11 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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: "Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma." in: The hematology journal : the official journal of the European Haematology Association / EHA, Vol. 2, Issue 1, pp. 42-53, (2002) (PubMed).
: "IL-4 prevents the blockade of dendritic cell differentiation induced by tumor cells." in: Cancer research, Vol. 61, Issue 7, pp. 3096-104, (2001) (PubMed).
: "STAT3 is constitutively activated in Hodgkin cell lines." in: Blood, Vol. 98, Issue 3, pp. 762-70, (2001) (PubMed).
: "Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors." in: Leukemia, Vol. 14, Issue 1, pp. 188-97, (2000) (PubMed).
: "Inhibition of the differentiation of dendritic cells from CD34(+) progenitors by tumor cells: role of interleukin-6 and macrophage colony-stimulating factor." in: Blood, Vol. 92, Issue 12, pp. 4778-91, (1999) (PubMed).
: "Toward a role of dendritic cells in the germinal center reaction: triggering of B cell proliferation and isotype switching." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 162, Issue 6, pp. 3428-36, (1999) (PubMed).
: "Critical role of IL-12 in dendritic cell-induced differentiation of naive B lymphocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 161, Issue 5, pp. 2223-31, (1998) (PubMed).
: "Pattern of cytokine receptors expressed by human dendritic cells migrated from dermal explants." in: Immunology, Vol. 91, Issue 2, pp. 303-13, (1997) (PubMed).
: "Purification and characterization of the soluble interleukin-6 receptor from human plasma and identification of an isoform generated through alternative splicing." in: European journal of biochemistry / FEBS, Vol. 236, Issue 3, pp. 837-42, (1996) (PubMed).
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: "Gp130 and ras mediated signaling in human plasma cell line INA-6: a cytokine-regulated tumor model for plasmacytoma." in: The hematology journal : the official journal of the European Haematology Association / EHA, Vol. 2, Issue 1, pp. 42-53, (2002) (PubMed).
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- IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))
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别名
- CD126
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背景
- IL-6R / gp80
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分子量
- 80 kDa
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途径
- JAK/STAT Signaling, Autophagy, Growth Factor Binding, Cancer Immune Checkpoints
抗原
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