CD25 抗体
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北京 101111
Quick Overview for CD25 抗体 (ABIN1383666)
抗原
See all CD25 (IL2RA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognises the Interleukin 2 Receptor a chain (IL-2 Ra), a 55 kDa protein
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纯化方法
- Ion exchange chromatography
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过滤
- 0.22 μm filtered
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免疫原
- PHA activated T cells,Myeloma X63/AG.8653 x Balb/c spleen cells
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亚型
- IgG1 kappa
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Biological Activity Comment
- Inhibits mixed lymphocyte culture
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anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 201-268) antibody
IL2RA 适用: 人, 小鼠 FACS, WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 34-139) antibodyIL2RA 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 1B5D12 unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 22-213) antibodyIL2RA 适用: 人 WB, ELISA, ICC, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 34-139) antibodyIL2RA 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 22-245) antibodyIL2RA 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) antibodyIL2RA 适用: 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 42-183) antibodyIL2RA 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal IL2RA-2395 unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) antibodyIL2RA 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-181 unconjugated
anti-Interleukin 2 Receptor, alpha (IL2RA) antibody (PerCP)IL2RA 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-181 PerCP
anti-Interleukin 2 Receptor, alpha (IL2RA) (AA 22-235) antibodyIL2RA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
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储存液
- Without preservative
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储存条件
- 4 °C
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储存方法
- Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
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: "A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines." in: American journal of physiology. Cell physiology, Vol. 287, Issue 2, pp. C365-72, (2004) (PubMed).
: "Inhibitory and stimulatory effects of IL-10 on human CD8+ T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 7, pp. 3188-93, (1998) (PubMed).
: "Cytogenetic abnormalities in primary myelodysplastic syndrome are highly predictive of outcome after allogeneic bone marrow transplantation." in: Blood, Vol. 92, Issue 6, pp. 1910-7, (1998) (PubMed).
: "Successful treatment of invasive aspergillosis in chronic granulomatous disease by bone marrow transplantation, granulocyte colony-stimulating factor-mobilized granulocytes, and liposomal amphotericin-B." in: Blood, Vol. 92, Issue 8, pp. 2719-24, (1998) (PubMed).
: "Interleukin-15 triggers activation and growth of the CD8 T-cell pool in extravascular tissues of patients with acquired immunodeficiency syndrome." in: Blood, Vol. 90, Issue 3, pp. 1115-23, (1997) (PubMed).
: "Outcome of lymphocyte subsets and cytokines during combined CD4/anti-IL-2R monoclonal antibody therapy in kidney transplantation." in: Transplantation proceedings, Vol. 27, Issue 2, pp. 1672-3, (1995) (PubMed).
: "Sequential use of three monoclonal antibodies in corticosteroid-resistant acute GVHD: a multicentric pilot study including 15 patients." in: Bone marrow transplantation, Vol. 15, Issue 5, pp. 669-77, (1995) (PubMed).
: "CD4 and CD25 monoclonal antibody cocktail in kidney transplant rejection prophylaxis: clinical results of a pilot study." in: Transplantation proceedings, Vol. 27, Issue 2, pp. 1727-8, (1995) (PubMed).
: "Treatment of steroid-resistant acute graft-versus-host disease with an anti-IL-2-receptor monoclonal antibody (BT 563) in children who received T cell-depleted, partially matched, related bone marrow transplants." in: Bone marrow transplantation, Vol. 13, Issue 5, pp. 563-9, (1994) (PubMed).
: "Humanization of mouse anti-human IL-2 receptor antibody B-B10." in: Protein engineering, Vol. 7, Issue 3, pp. 435-43, (1994) (PubMed).
: "B-B10 (anti-CD25)-saporin immunotoxin--a possible tool in graft-versus-host disease treatment." in: Transplantation, Vol. 54, Issue 2, pp. 351-6, (1992) (PubMed).
: "[Therapy of multiple myeloma by allogeneic bone marrow transplantation]." in: Deutsche medizinische Wochenschrift (1946), Vol. 116, Issue 22, pp. 852-6, (1991) (PubMed).
: "Immunotoxins constructed with anti-CD25 monoclonal antibodies and deglycosylated ricin A-chain have potent anti-tumour effects against human Hodgkin cells in vitro and solid Hodgkin tumours in mice." in: International journal of cancer. Journal international du cancer, Vol. 49, Issue 3, pp. 450-6, (1991) (PubMed).
: "Soluble CD8, IL-2 receptor, and tumor necrosis factor-alpha levels in steroid-resistant acute graft-versus-host disease. Relation with subsequent response to anti-IL-2 receptor monoclonal antibody treatment." in: Transplantation, Vol. 52, Issue 3, pp. 475-80, (1991) (PubMed).
: "A semi-pharmaceutical approach for the preparation of an anti-IL2 receptor monoclonal antibody in the treatment of acute GvHD in a multicentric study." in: Developments in biological standardization, Vol. 71, pp. 103-11, (1990) (PubMed).
: "Treatment of corticosteroid resistant acute graft-versus-host disease by in vivo administration of anti-interleukin-2 receptor monoclonal antibody (B-B10)" in: Blood, Vol. 75, Issue 4, pp. 1017-23, (1990) (PubMed).
: "Treatment of acute graft-versus-host disease with monoclonal antibody to IL-2 receptor." in: Lancet, Vol. 2, Issue 8619, pp. 1072-3, (1988) (PubMed).
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: "A dileucine motif targets the sulfate anion transporter sat-1 to the basolateral membrane in renal cell lines." in: American journal of physiology. Cell physiology, Vol. 287, Issue 2, pp. C365-72, (2004) (PubMed).
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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别名
- CD25
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背景
- IL-2R α-Chain
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分子量
- 55 kDa
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途径
- JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
抗原
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