CD51 抗体 (PE)
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北京 101111
Quick Overview for CD51 抗体 (PE) (ABIN135793)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Human/African Green Monkey/Rabbit/Bovine CD51, Mr 125 & 24 kDa
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产品特性
- Mouse Anti-Human CD51-PE
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免疫原
- Cell suspension containing osteoclasts from osteoclastomas
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亚型
- IgG1
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应用备注
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Working Dilution:
FACS: 10 µL/10^6 cells
Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded. -
限制
- 仅限研究用
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缓冲液
- Product is supplied as 100 tests in 1.0 mL of PBS / NaN3 and a stabilizing agent.
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注意事项
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Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed. -
储存条件
- 4 °C
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- CD51
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背景
- CD51 represents the 150 kDa integrin V chain that associates with integrin 3 (CD61) to form the CD51/CD61 vitronectin receptor on endothelial cells, certain activated leukocytes, NK cells, macrophages, neutrophils and platelets. CD51 is the most promiscuous integrin a subunit, it can form heterodimers with the 1 (CD29), 3 (CD61), 5, 6 and 8 subunits in various tissues. CD51/CD61 acts as an activation-independent receptor for platelet attachment and spreading on vitronectin and other RGD-containing proteins, including matrix components. It also mediates leukocyte-endothelial cell adhesion via interaction with CD31.
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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