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MCAM 抗体

MCAM 适用: 小鸡 FACS 宿主: 小鼠 Monoclonal C264 unconjugated
产品编号 ABIN135586
发货至: 中国
  • 抗原 See all MCAM 抗体
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    适用
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    小鸡
    宿主
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    小鼠
    克隆类型
    • 87
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    单克隆
    标记
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    This MCAM antibody is un-conjugated
    应用范围
    • 89
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    Flow Cytometry (FACS)
    特异性
    Chicken/Turkey MCAM, Mr 98 kDa
    产品特性
    Mouse Anti-Chicken MCAM-UNLB
    纯化方法
    Purified
    免疫原
    Mixture of E15 and E16 thymocytes from H.B15, H.B19, and H.B21 chicken embryos
    克隆位点
    C264
    亚型
    IgG2b
    Top Product
    Discover our top product MCAM Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , ICC - Reported in literature , IP - Reported in literature
    • Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • 抗原
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    别名
    MCAM (MCAM 产品)
    别名
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    背景
    Chicken MCAM, a member of the immunoglobulin superfamily of cell surface receptors, consists of the V-V-C2-C2-C2 Ig domains. It is a single chain glycoprotein with three mRNA splice variants. One has a short cytoplasmic tail, another has a long tail, and the third seems to lack transmembrane and cytoplasmic regions. It is highly homologous to gicerin, a molecule involved in neurite outgrowth and Wilm's kidney tumor progression in the chicken, and to the human melanoma progression molecule MUC18. Chicken MCAM is expressed by c-kit+ hematopoietic progenitor cells in embryonic bone marrow, thymocytes, and capillary endothelial cells. MCAM-expressing cells sorted from bone marrow are enriched in progenitors capable of differentiating into T cells when transferred into the appropriate thymic microenvironment. MCAM has been proposed to be involved in cellular adhesion and homing processes.
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