CD25 抗体
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北京 101111
Quick Overview for CD25 抗体 (ABIN135175)
抗原
See all CD25 (IL2RA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Rat Anti-Mouse CD25-LE/AF
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特异性
- Mouse CD25, Mr 55 kDa
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产品特性
- Low Endotoxin/Azide Free Anti-Mouse CD25 antibody for use in flow cytometry, immunohistochemistry, immunoprecipitation, blocking, depletion, CMCD, and neutralization assays.
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内毒素水平
- Low Endotoxin
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免疫原
- IL-2 dependent BALB/c helper T cell clone HT2
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亚型
- IgM
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline, pH 7.4
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储存液
- Azide free
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- 2-8°C
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- CD25 (IL2RA) (Interleukin 2 Receptor, alpha (IL2RA))
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别名
- CD25
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背景
- The IL-2 receptor (IL-2R) exists in three alternative forms made up from the individual components of CD25, CD122, and CD132. CD25 represents the low affinity chain of the IL-2R, a type I transmembrane glycoprotein containing two CCP domains. It is rich in O-linked carbohydrates and has a short cytoplasmic tail. CD25 is expressed on activated T cells, B cells, NK cells and monocytes of all mouse strains tested. It is transiently expressed at a low level during B-cell development in bone marrow on the CD45R/B220low TdT- sIg- pre-B II and CD45R/B220low TdT- sIgM+sIgD- immature B cells, but not on the CD45R/B220low TdT+ sIg- pro-B/pre-B I stage nor on CD45R/B220high TdT- sIgM+sIgD+ mature B cells. CD25 is expressed at a higher level during very early T-cell development in fetal and adult thymus.
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基因ID
- 16184
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UniProt
- P01590
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途径
- JAK/STAT Signaling, Growth Factor Binding, Activated T Cell Proliferation
抗原
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