FCER2 抗体
Quick Overview for FCER2 抗体 (ABIN135164)
抗原
See all FCER2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mouse CD23, Mr 45-49 kDa
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产品特性
- Rat Anti-Mouse CD23-UNLB
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纯化方法
- Purified
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免疫原
- FcR isolated from B cell lymphoma cell line M12.4.5
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亚型
- IgG2a
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应用备注
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- Applications: FC - Quality tested , IHC-FS - Reported in literature , ELISA - Reported in literature
- Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC and BIOT conjugates 1 g/106 cells PE, APC, and PE/CY7 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
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说明
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cell sorting
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样本量
- 1 mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- 0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added
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储存液
- Without preservative
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注意事项
- Each reagent is stable for the period shown on the bottle label if stored as directed.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C
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- FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
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别名
- CD23
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背景
- The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages and platelets. It is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a membrane bound cytokine, in that the soluble cleavage products of CD23 are themselves able to act as cytokines in vitro.
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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