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CD3 epsilon 抗体

This 仓鼠 单克隆 antibody specifically detects CD3 epsilon in FACS. It exhibits reactivity toward 小鼠.It has been mentioned in 1 publication
产品编号 ABIN135085
发货至: 中国
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Quick Overview for CD3 epsilon 抗体 (ABIN135085)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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小鼠

宿主

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仓鼠

克隆类型

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单克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Flow Cytometry (FACS)

克隆位点

145-2C11
  • 特异性

    Mouse CD3, Mr 25 kDa

    产品特性

    Hamster Anti-Mouse CD3e-UNLB

    纯化方法

    Purified

    免疫原

    H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone BM10-37

    亚型

    IgG
  • 应用备注

    • Applications: FC - Quality tested , IHC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Depletion - Reported in literature , Activ - Reported in literature , CMCD - Reported in literature
    • Working Dilutions: Flow Cytometry FITC conjugate 3 g/106 cells BIMA and AF488 conjugates 1 g/106 cells PE, APC, SPRD, and AF647 conjugates 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 l

    说明

    In vitro depletion of CD3+ cells, In vitro activation of T cells

    样本量

    1 mL

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added

    储存液

    Without preservative

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C
  • Ershaid, Sharon, Doron, Raz, Shani, Cohen, Monteran, Leider-Trejo, Ben-Shmuel, Yassin, Gerlic, Ben-Baruch, Pasmanik-Chor, Apte, Erez: "NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis." in: Nature communications, Vol. 10, Issue 1, pp. 4375, (2020) (PubMed).

  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3e

    背景

    CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation.

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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