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CD44 抗体

The 大鼠 单克隆 anti-CD44 antibody (Clone KM201) (ABIN135069) specifically detects CD44 in FACS, WB, IHC (p), IP, IHC (fro), ICC, BR 和 Adh Act. The antibody is reactive with 小鼠 samples.
产品编号 ABIN135069
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD44 抗体 (ABIN135069)

抗原

See all CD44 抗体
CD44

适用

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小鼠

宿主

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大鼠

克隆类型

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单克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Blocking Reagent (BR), Adhesion Activation (Adh Act)

克隆位点

KM201
  • 原理

    Rat Anti-Mouse CD44-LE/AF

    特异性

    Mouse CD44 (all isoforms), Mr 80-95 kDa

    产品特性

    Low Endotoxin/Azide Free Anti-Mouse CD44 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, blocking, and adhesion assays.

    内毒素水平

    Low Endotoxin

    免疫原

    (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline, pH 7.4

    储存液

    Azide free

    注意事项

    Each reagent is stable for the period shown on the bottle label if stored as directed.

    储存条件

    4 °C

    储存方法

    2-8°C
  • 抗原

    CD44

    别名

    CD44

    背景

    CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.

    基因ID

    12505

    UniProt

    P15379

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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