电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

CD44 抗体

CD44 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal KM201 unconjugated
产品编号 ABIN135065
发货至: 中国
  • 抗原 See all CD44 抗体
    CD44
    适用
    • 284
    • 146
    • 81
    • 30
    • 25
    • 24
    • 16
    • 11
    • 9
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 159
    • 122
    • 71
    • 2
    • 1
    大鼠
    克隆类型
    • 237
    • 116
    • 2
    单克隆
    标记
    • 157
    • 39
    • 30
    • 24
    • 17
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD44 antibody is un-conjugated
    应用范围
    • 251
    • 149
    • 92
    • 72
    • 68
    • 65
    • 58
    • 40
    • 34
    • 31
    • 27
    • 13
    • 7
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    特异性
    Mouse CD44 (all isoforms), Mr 80-95 kDa
    产品特性
    Rat Anti-Mouse CD44-UNLB
    纯化方法
    Purified
    免疫原
    (C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2
    克隆位点
    KM201
    亚型
    IgG1
    Top Product
    Discover our top product CD44 Primary Antibody
  • 应用备注
    • Applications: FC - Quality tested , IHC-FS - Reported in literature , IHC-PS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , WB - Reported in literature , Block - Reported in literature , Adhesion - Reported in literature
    • Working Dilutions: Flow Cytometry FITC and BIOT conjugates 2 g/106 cells PE, APC, and SPRD conjugates 0.2 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L
    说明

    cell adhesion and homing

    样本量
    1 mL
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    0.5 mg of purified immunoglobulin in 1.0 mL of borate buffered saline,  pH 8.2. No preservatives or amine-containing buffer salts added
    储存液
    Without preservative
    注意事项
    Each reagent is stable for the period shown on the bottle label if stored as directed.
    储存条件
    4 °C
    储存方法
    Store at 2-8°C
  • Rux, Song, Swinehart, Pineault, Schlientz, Trulik, Goldstein, Kozloff, Lucas, Wellik: "Regionally Restricted Hox Function in Adult Bone Marrow Multipotent Mesenchymal Stem/Stromal Cells." in: Developmental cell, Vol. 39, Issue 6, pp. 653-666, (2017) (PubMed).

    Goldman, Majumder, Dhawan, Ravi, Goldman, Kohandel, Majumder, Sengupta: "Temporally sequenced anticancer drugs overcome adaptive resistance by targeting a vulnerable chemotherapy-induced phenotypic transition." in: Nature communications, Vol. 6, pp. 6139, (2016) (PubMed).

    Sánchez, Hill, Love, Soslow, Craig, Austin, Brown, Czirok, Camenisch, Barnett: "The cytoplasmic domain of TGFβR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior." in: Developmental biology, Vol. 358, Issue 2, pp. 331-43, (2011) (PubMed).

  • 抗原
    CD44
    别名
    CD44 (CD44 产品)
    别名
    CDW44 antibody, CSPG8 antibody, ECMR-III antibody, HCELL antibody, HUTCH-I antibody, IN antibody, LHR antibody, MC56 antibody, MDU2 antibody, MDU3 antibody, MIC4 antibody, Pgp1 antibody, AU023126 antibody, AW121933 antibody, AW146109 antibody, HERMES antibody, Ly-24 antibody, Pgp-1 antibody, CD44A antibody, METAA antibody, RHAMM antibody, XCD44 antibody, cd44 antibody, cdw44 antibody, cspg8 antibody, ecmr-iii antibody, hcell antibody, lhr antibody, mc56 antibody, mdu2 antibody, mdu3 antibody, mic4 antibody, mutch-i antibody, pgp1 antibody, CD44 molecule (Indian blood group) antibody, syndecan 4 antibody, CD44 antigen antibody, CD44 molecule (Indian blood group) S homeolog antibody, CD44 antibody, SDC4 antibody, Cd44 antibody, cd44.S antibody
    背景
    CD44 represents a family of type I transmembrane glycoproteins expressed on many cell types such as B cells, monocytes, macrophages, and variable subsets of thymocytes and peripheral T cells. CD44 primarily functions as an adhesion molecule. It has been implicated in various processes, such as hematopoiesis, lymphocyte homing, leukocyte activation, tumor metastasis and development. The KM201 monoclonal antibody reacts with an epitope very close to the hyaluronate binding domain on the CD44 molecule. KM201 can inhibit hyaluronate-dependent cell aggregation, prevent lympho-hemopoiesis in both Dexter and Whitlock-Witte Cultures, prevent the earliest intrathymic precursors from homing to the thymus, and costimulate the activation of freshly purified splenic CD4+ T cells.
    途径
    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
You are here:
客服