CCDC98 抗体 (AA 1-313)
Quick Overview for CCDC98 抗体 (AA 1-313) (ABIN1302443)
抗原
See all CCDC98 (FAM175A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-313
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原理
- Anti-ABRA1 Purified
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特异性
- The mouse monoclonal antibody ABRA1-01 recognizes human ABRA1 (Abraxas, CCDC98), an adaptor protein involved in DNA repair, which migrates as a 45 kDa band on PAAGE under reducing conditions.
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交叉反应 （详细）
- Human, Other not tested
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag
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亚型
- IgG2a kappa
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anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 51-150) antibody
FAM175A 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 350-400) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (N-Term) antibodyFAM175A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow cytometry: Recommended dilution: 1-2 μg/mL. Intracellular staining.
Western blotting: Reducing conditions. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
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别名
- ABRA1
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背景
- Abraxas 1, BRCA1 A complex subunit,ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation.,ABRA1, Abraxas 1, CCDC98, FAM175A
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基因ID
- 84142
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UniProt
- Q6UWZ7
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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