FANCA 抗体 (AA 995-1009)
(1 reference)
Quick Overview for FANCA 抗体 (AA 995-1009) (ABIN129606)
抗原
See all FANCA 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 995-1009
-
Supplier Product No.
- 600-401-670
-
Supplier
- Rockland
-
原理
- FANCA Antibody
-
交叉反应 （详细）
- This affinity-purified antibody is directed against human FANCA protein.
-
产品特性
- Synonyms: rabbit anti-FANCA antibody, FANC-A, FANC A, Fanconi anemia group A protein, FAA antibody, FACA antibody, FAH antibody, FANCH antibody
-
纯化方法
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
-
过滤
- Sterile filtered
-
免疫原
-
Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein.
Immunogen Type: Conjugated Peptide
-
亚型
- IgG
-
-
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibody
FANCA 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-297) antibodyFANCA 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1121-1170), (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (pSer1149) antibodyFANCA 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 609-813) antibodyFANCA 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (N-Term) antibodyFANCA 适用: 人 WB, IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 71-120) antibodyFANCA 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (AA 1-275) antibodyFANCA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) antibodyFANCA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Fanconi Anemia Group A Protein (FANCA) (C-Term), (pSer1149) antibodyFANCA 适用: 人, 大鼠, 小鼠 WB, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Application Note: This affinity purified antibody has been tested for use in ELISA and by western blot. Specific conditions for reactivity should be optimized by the end user. Expect a main band at approximately 163 kDa in size corresponding to FANCA by western blotting in the appropriate cell lysate or extract or human tissue.
Western Blot Dilution: 1:500 - 1:3,000
ELISA Dilution: 1:15,000 - 1:60,000
Other: User Optimized
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 2.2 mg/mL
-
缓冲液
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
有效期
- 12 months
-
-
-
: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
-
: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
-
- FANCA (Fanconi Anemia Group A Protein (FANCA))
-
别名
- FANCA
-
背景
- Background: FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Diseases associated with FANCA include Fanconi anemia complementation group a and Congenital Hypoplastic Anemia.
-
基因ID
- 2175, 66880553
-
UniProt
- O15360
-
途径
- DNA Damage Repair
抗原
-
