Phospholipase C gamma 1 抗体
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Quick Overview for Phospholipase C gamma 1 抗体 (ABIN127317)
抗原
See all Phospholipase C gamma 1 (PLCG1) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody recognizes 139 kDa human PLCγ 1&2.
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纯化方法
- Protein A affinity purified
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免疫原
- Synthetic peptide surrounding amino acid 1252 of human PLCgamma2
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anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibody
PLCG1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1091-1290) antibodyPLCG1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr771) antibodyPLCG1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibodyPLCG1 适用: 人, 大鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3C2D11 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 1192-1291) antibodyPLCG1 适用: 人, 小鼠 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 3H1C10 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (AA 39-181) antibodyPLCG1 适用: 人, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2F3D11 unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr783) antibodyPLCG1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (pTyr783) antibodyPLCG1 适用: 小鼠, 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) (Tyr771) antibodyPLCG1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-phospholipase C, gamma 1 (PLCG1) antibodyKD Validated PLCG1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB2080 unconjugated Recombinant Antibody
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应用备注
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Western Blot: 0.5-4 μg/mL, Jurkat cell lysate can be used as a positive control.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
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别名
- PLCG1
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背景
- PLC (Phosphoinositide-specific phospholipase C) plays a significant role in transmembrane signaling. Four members of PLCs have been identified: PLCβ, PLCγ, PLCδ, and PLCε. In response to extracellular stimuli (e.g., hormone, growth factors, neurotransmitters), PLC hydrolizes phosphatidylinositol 4,5-biphosphate (PIP2) into two secondary messengers: inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG). PLCγ2 is engaged in antigendependent signaling in B-cells and collagen-dependent signaling in platelets.Synonyms: 1-phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma-1, 5-bisphosphate phosphodiesterase gamma-2, PLC-148, PLC-II, PLC-IV, PLC-gamma-1, PLC-gamma-2, PLC1, PLCG-1, PLCG-2, PLCgamma2, Phospholipase C-gamma-1, Phospholipase C-gamma-2
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基因ID
- 5335
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NCBI登录号
- NP_877963
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UniProt
- P19174
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途径
- RTK signaling, WNT signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Inositol Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Skeletal Muscle Fiber Development, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, VEGFR1 Specific Signals, VEGF Signaling
抗原
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