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FKBP1A 抗体

This anti-FKBP1A antibody is a 兔 多克隆 antibody detecting FKBP1A in WB, IP 和 IHC (p). Suitable for 人, 小鼠, 大鼠, Cow 和 兔.
产品编号 ABIN127265
发货至: 中国

Quick Overview for FKBP1A 抗体 (ABIN127265)

抗原

See all FKBP1A 抗体
FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

适用

  • 64
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人, 小鼠, 大鼠, Cow, 兔

宿主

  • 64
  • 9

克隆类型

  • 55
  • 18
多克隆

标记

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  • 10
  • 9
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  • 1
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This FKBP1A antibody is un-conjugated

应用范围

  • 43
  • 30
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  • 10
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  • 4
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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 特异性

    The antibody detects 12 kDa FKBP12 protein.

    纯化方法

    Affinity purified

    免疫原

    Synthetic peptide surrounding amino acid 10 of human FKBP1A/FKBP12.
  • 应用备注

    Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 2-10 μg/mL. Immunohistochemistry: 2-10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原

    FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

    别名

    FKBP1A / FKBP12

    背景

    FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase

    基因ID

    2280

    NCBI登录号

    NP_000792

    UniProt

    P62942

    途径

    Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
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