FKBP1A 抗体
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北京 101111
Quick Overview for FKBP1A 抗体 (ABIN127265)
抗原
See all FKBP1A 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- The antibody detects 12 kDa FKBP12 protein.
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纯化方法
- Affinity purified
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免疫原
- Synthetic peptide surrounding amino acid 10 of human FKBP1A/FKBP12.
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应用备注
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Western Blot: 0.5-4 μg/mL. Immunoprecipitation: 2-10 μg/mL. Immunohistochemistry: 2-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C/-80 °C
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储存方法
- Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
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- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
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别名
- FKBP1A / FKBP12
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背景
- FKBP12 is a member of the family of soluble receptors capable of binding to one of two major immunosuppressant agents. FKBP12 also plays a role in intracellular calcium regulation by associating with three types of calcium release channel complexes, cardiac and skeletal ryanodine receptors and the inositol 1,4,5-trisphosphate receptor. In interactions with members of the TGF beta family type I receptors, FKBP12 has been shown to exert an inhibitory effect on the signaling pathway.Synonyms: FK506-binding protein 1A, Immunophilin FKBP12, PPIase FKBP1A, Peptidyl-prolyl cis-trans isomerase FKBP1A, Rotamase
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基因ID
- 2280
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NCBI登录号
- NP_000792
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UniProt
- P62942
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途径
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
抗原
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