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PAK4 抗体 (N-Term)

PAK4 适用: 人, 小鼠, 大鼠 WB, IP, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN127123
发货至: 中国
  • 抗原 See all PAK4 抗体
    PAK4 (P21-Activated Kinase 4 (PAK4))
    抗原表位
    • 13
    • 9
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 85
    • 54
    • 35
    • 7
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    人, 小鼠, 大鼠
    宿主
    • 79
    • 5
    • 1
    克隆类型
    • 80
    • 5
    多克隆
    标记
    • 41
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PAK4 antibody is un-conjugated
    应用范围
    • 69
    • 38
    • 19
    • 19
    • 9
    • 7
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    The antibody recognizes 72 kDa Pak4. It does not cross-react with other Paks.
    纯化方法
    Antigen affinity purified
    免疫原
    Synthetic peptide corresponding to the N-terminus of human Pak4
    Top Product
    Discover our top product PAK4 Primary Antibody
  • 应用备注
    Western Blot: 1 μg/mL. Immunoprecipitation: 20 μg/mL. Immunohistochemistry: 20 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    PBS containing 50 % glycerol, 1 % BSA, and 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    PAK4 (P21-Activated Kinase 4 (PAK4))
    别名
    PAK4 (PAK4 产品)
    别名
    5730488L07Rik antibody, AW555722 antibody, mKIAA1142 antibody, im:5916170 antibody, wu:fd12b01 antibody, zgc:92014 antibody, p21 (RAC1) activated kinase 4 antibody, p21 protein (Cdc42/Rac)-activated kinase 4 antibody, PAK4 antibody, Pak4 antibody, pak4 antibody
    背景
    The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. Several mechanisms that induce PAK activation have been reported. Binding of Rac/cdc42 to the CRIB (or PBD) domain at the N-terminal region of PAK causes autophosphorylation and conformational change of PAK. More recently identified members PAK4, PAK5 and PAK6 have lower sequence similarity with PAK1-3 in the regulatory N-terminal region. It has been demonstrated that phosphorylation of serine 474 of PAK4 may play a pivotal role in the activity and function of PAK4 kinase.Synonyms: KIAA1142, PAK 4, PAK-4, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4
    基因ID
    10298
    NCBI登录号
    NP_001014831
    UniProt
    O96013
    途径
    RTK signaling
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