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CD40 Ligand 抗体

The 兔 多克隆 anti-CD40 Ligand antibody is suitable to detect CD40 Ligand in samples from 人, 小鼠 和 大鼠. It has been validated for WB.
产品编号 ABIN127037
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD40 Ligand 抗体 (ABIN127037)

抗原

See all CD40 Ligand (CD40LG) 抗体
CD40 Ligand (CD40LG)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This CD40 Ligand antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody detects CD40L.

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide surrounding amino acid 246 of human CD40 Ligand
  • 应用备注

    Western blot (0.5-4 μg/mL). Recommended positive control: Jurkat cell lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid Repeated freeze/defrost cycles.

    储存条件

    -20 °C

    储存方法

    Store (in aliquots) at -20 °C.
  • 抗原

    CD40 Ligand (CD40LG)

    别名

    CD154 / CD40L

    背景

    CD40 is a type I membrane protein found on the surface of B cells and primary carcinomas. It belongs to the TNF-R family. CD40 serves as the receptor for CD40 ligand (CD40L), a cytokine expressed on the cell surface of T cells. CD40 plays a critical role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with T cells expressing CD40L, and activation of CD4+ T cells. Ligation of CD40 with its ligand preferentially induces stress-activated protein kinases in B lymphocytes.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5

    基因ID

    959

    NCBI登录号

    NP_000065

    UniProt

    P29965

    途径

    NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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