MAPK14 抗体 (N-Term)
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Quick Overview for MAPK14 抗体 (N-Term) (ABIN127010)
抗原
See all MAPK14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- The antibody detects p38 MAP kinase. It does not cross-react with either JNK/SAPK or p44/42 MAP kinase.
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纯化方法
- Affinity Purified
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免疫原
- Synthetic peptide mapping to the N-terminus of human p38 MAP kinase
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应用备注
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Western blotting (0.5-4.0 μg/mL). Immunoprecipitation (10-20 μg/mL). Immunohistochemistry (10-20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 30 % glycerol, 0.5 % BSA, and 0.01 % thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store undiluted (in aliquots) at -20 °C to -70 °C.
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- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
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别名
- MAP Kinase p38 alpha / MAPK14
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背景
- P38 MAP kinase is the mammalian homologue of the yeast HOG kinase and participates in a cascade controlling cell cellular responses to cytokines and stress. Like the SAPK/JNK pathway, p38 MAP kinase is activated by a variety of cellular stresses including inflammatory cytokines, UV light and growth factors, etc. Activated p38 MAP kinase has been shown to phosphorylate and activate MAPKAP kinase-2 and to phosphorylate the transcription factors ATF-2 and Max.Synonyms: CSBP, CSBP1, CSBP2, CSPB1, Cytokine suppressive anti-inflammatory drug-binding protein, MAX-interacting protein 2, MXI2, Mitogen-activated protein kinase 14, SAPK2A, p38 alpha
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基因ID
- 1432
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NCBI登录号
- NP_001306
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UniProt
- Q16539
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
抗原
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