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FADD 抗体

FADD 适用: 人, 小鼠, 大鼠 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126986
发货至: 中国
  • 抗原 See all FADD 抗体
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    适用
    • 86
    • 59
    • 19
    • 18
    • 15
    人, 小鼠, 大鼠
    宿主
    • 95
    • 17
    克隆类型
    • 93
    • 19
    多克隆
    标记
    • 64
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FADD antibody is un-conjugated
    应用范围
    • 86
    • 50
    • 31
    • 15
    • 15
    • 12
    • 11
    • 8
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    特异性
    The antibody detects an ~28 kDa band, corresponding to the expected molecular mass of FADD on immunoblots. The antibody specificity is confirmed by specific peptide inhibition in immunoblotting studies.
    纯化方法
    Affinity chromatography
    免疫原
    Synthetic peptide surrounding amino acid 128 of human FADD
    Top Product
    Discover our top product FADD Primary Antibody
  • 应用备注
    Western Blot: 0.5-4 μg/mL. Based on researcher's feedback, it can also be used in immunoprecipitation.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2, containing 30 % glycerol, 0.5 % BSA, 0.01 % thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody undiluted (in aliquots) at -20 °C to -70 °C.
  • 抗原
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    别名
    FADD (FADD 产品)
    别名
    MORT1 antibody, Mort1/FADD antibody, Mort1 antibody, TNFRSF6 antibody, adaptor antibody, fadd antibody, mort1 antibody, xfadd antibody, Fas associated via death domain antibody, Fas (TNFRSF6)-associated via death domain antibody, Fas associated via death domain S homeolog antibody, Fas (tnfrsf6)-associated via death domain antibody, FADD antibody, Fadd antibody, fadd.S antibody, fadd antibody
    背景
    Fas-associating death domain containing protein (FADD), also known as mediator of receptor induced toxicity (MORT1), is a 23 kDa cytosolic protein with an apparent molecular weight of 28 kDa on SDS-PAGE. The protein is involved in both Fas and TNF-R induced cell death pathway. FADD specifically binds to Fas to initiate the apoptotic signalling cascade. Overexpression of FADD induces apoptosis.Synonyms: FAS-associated death domain protein, FAS-associating death domain-containing protein, GIG3, Growth-inhibiting gene 3 protein, MORT1, Mediator of receptor induced toxicity
    基因ID
    8772
    NCBI登录号
    NP_003815
    UniProt
    Q13158
    途径
    Apoptosis, TLR signaling, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
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