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Caspase 2 抗体

CASP2 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN126971
发货至: 中国
  • 抗原 See all Caspase 2 (CASP2) 抗体
    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
    适用
    • 95
    • 36
    • 24
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 87
    • 6
    • 4
    克隆类型
    • 77
    • 20
    多克隆
    标记
    • 55
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Caspase 2 antibody is un-conjugated
    应用范围
    • 69
    • 33
    • 22
    • 14
    • 14
    • 11
    • 9
    • 7
    • 6
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB)
    特异性
    Detects the full length and small subunit of caspase-2. In Human samples, it also detects a 30 kDa intermediate fragment.
    纯化方法
    Affinity Chromatography
    免疫原
    Synthetic peptide surrounding amino acid 417 of Mouse Caspase-2
    Top Product
    Discover our top product CASP2 Primary Antibody
  • 应用备注
    Western Blot: 1-2 μg/mLMouse small intestine lysate can be used as a Positive Control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    0.2 mg/mL
    缓冲液
    PBS, pH 7.2, containing 30 % Glycerol, 0.5 % BSA and 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C/-80 °C
    储存方法
    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C.
  • 抗原
    Caspase 2 (CASP2) (Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
    别名
    Caspase-2 (CASP2 产品)
    别名
    xCaspase-2 antibody, Caspase-2 antibody, ICH-1 antibody, Nedd2 antibody, CASP-2 antibody, ICH1 antibody, NEDD-2 antibody, NEDD2 antibody, PPP1R57 antibody, ICH-1L/1S antibody, ICH1L1S antibody, caspase 2 antibody, caspase 2 L homeolog antibody, caspase-2 antibody, CASP2 antibody, casp2.L antibody, CpipJ_CPIJ008254 antibody, Casp2 antibody
    背景
    Caspases play a key role in apoptosis. Similar as other caspases, caspase-2 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Caspase-2 mRNA is alternatively spliced. The larger mRNA species encoding a product of 435 amino acids is known as ICH-1L. The smaller mRNA species encoding a protein of 312 amino acids is named ICH-1S. Over expression of ICH-1L induces apoptosis, while over expression of ICH-1S suppresses Rat-1 cell death induced by serum deprivation.Synonyms: CASP-2, CASP2, ICH-1 protease, ICH1, NEDD2, Neural precursor cell expressed developmentally down-regulated protein 2
    基因ID
    835
    NCBI登录号
    NP_001215
    UniProt
    P42575
    途径
    Apoptosis, Caspase Cascade in Apoptosis, Neurotrophin Signaling Pathway
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