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MAPT 抗体 (Isoform 13, N-Term)

This anti-MAPT antibody is a 小鼠 单克隆 antibody detecting MAPT in WB, IP 和 IHC (p). Suitable for 人.
产品编号 ABIN126938
发货至: 中国

Quick Overview for MAPT 抗体 (Isoform 13, N-Term) (ABIN126938)

抗原

See all MAPT 抗体
MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This MAPT antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

C45
  • 抗原表位

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    Isoform 13, N-Term

    产品特性

    Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, PHF-tau, Neurofibrillary tangle protein,Paired helical filament-tau

    纯化方法

    Affinity Purified

    免疫原

    Synthetic peptide corresponding to the N-terminus of of the longest isoform of Human Tau.

    亚型

    IgG1
  • 应用备注

    Western Blot: 1/1000. Immunoprecipitation: 1/500. Immunohistochemistry: 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS containing 50 % Glycerol, 1 % BSA and 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store the antibody undiluted at -20 °C or for long term storage (in aliquots) at -70 °C. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    MAPT (Microtubule-Associated Protein tau (MAPT))

    别名

    MAPT / tau

    背景

    Tau, a microtubule-binding protein which serves to stabilize microtubules in growing axons, is found to be hyperphosphorylated in paired helical filaments (PHF), the major fibrous component of neurofibrillary lesions associated with Alzheimers disease. Hyperphosphorylation of Tau is thought to be the critical event leading to the assembly of PHF. Six Tau protein isoforms have been identified, all of which are phosphorylated by GSK3. This presents the possibility that miscues in GSK3 signaling contribute to the onset of Alzheimers disease.Synonyms: MAPTL, MTBT1, Microtubule-associated protein tau, Neurofibrillary tangle protein, PHF-tau, Paired helical filament-tau

    UniProt

    P10636

    途径

    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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