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AKT1 抗体 (AA 107-122)
AKT1
适用: 人, 大鼠, 犬
WB, EIA, IHC (fro)
宿主: 小鼠
Monoclonal
5G12
unconjugated
AKT1抗体详情
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抗原
See all AKT1 抗体
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
抗原表位
All epitopes for AKT1 抗体
AA 107-122
适用
All reactivities for AKT1 抗体
人, 大鼠, 犬
宿主
All hosts for AKT1 抗体
小鼠
克隆类型
All clonalities for AKT1 抗体
单克隆
标记
All conjugates for AKT1 抗体
This AKT1 antibody is un-conjugated
应用范围
All applications for AKT1 抗体
Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
特异性
This antibody specifically recognizes the alpha isoform of PKB (PKBα/Akt1).
产品特性
Synonyms: Akt-1, RAC-PK-alpha, Protein kinase B, C-AKT, RAC-alpha serine/threonine-protein kinase
纯化方法
Subsequent Thiophilic Adsorption and Size Exclusion Chromatography
组件
incl. positive Control
免疫原
Synthetic peptide conjugated to KLH. Epitope: aa 107-122
克隆位点
5G12
亚型
IgG1
Top Product
Discover our top product AKT1 Primary Antibody
Alternatives
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使用细节
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应用备注
Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended buffer: Casein/Tween 20 based blocking and blot incubation buffer. Recommended positive control: Cell lysate from untreated Neuro2A cells. The antiboby crossreacts in immunoblot applications with an unknown protein of ca.120 kDa expressed in human tumor cell lines. ELISA: 0.05 μg/mL. Immunohistochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
贮存及处理
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浓度
0.1 mg/mL
缓冲液
PBS containing 0.09 % Sodium Azide, PEG and Sucrose/50 % Glycerol
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
-20 °C
储存方法
Store the antibody at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
有效期
12 months
AKT1目标详情
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抗原
AKT1
(V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
别名
AKT1 / PKB (AKT1 产品 )
别名
AKT antibody, CWS6 antibody, PKB antibody, PKB-ALPHA antibody, PRKBA antibody, RAC antibody, RAC-ALPHA antibody, Akt antibody, Rac antibody, PKB/Akt antibody, PKBalpha antibody, AKT/PKB antibody, AKT1 antibody, Akt/PKB antibody, Akt1 antibody, CG4006 antibody, D-Akt antibody, DAKT1 antibody, DAKT1/PKB antibody, DAkt antibody, DAkt1 antibody, DPKB antibody, DRAC-PK antibody, DRAC-PK66 antibody, DRAC-PK85 antibody, Dakt antibody, Dakt1 antibody, Dmel\\CG4006 antibody, Dpkb antibody, PKB/AKT antibody, PKB/dAKT antibody, RacPK antibody, akt antibody, akt1 antibody, dAKT antibody, dAKT/dPKB antibody, dAKT1 antibody, dAkt antibody, dAkt/PKB antibody, dAkt1 antibody, dPKB antibody, dakt antibody, dakt1 antibody, l(3)04226 antibody, l(3)89Bq antibody, p-Akt antibody, pAkt antibody, ACT-5 antibody, akt-1 antibody, pkb antibody, v-akt antibody, v-akt1 antibody, xAct antibody, ATAKT1 antibody, F18A8.2 antibody, F18A8_2 antibody, K+ transporter 1 antibody, POTASSIUM TRANSPORTER antibody, AKT serine/threonine kinase 1 antibody, thymoma viral proto-oncogene 1 antibody, CG4006 gene product from transcript CG4006-RE antibody, actin beta antibody, v-akt murine thymoma viral oncogene homolog 1 S homeolog antibody, v-akt murine thymoma viral oncogene homolog 1 antibody, K+ transporter 1 antibody, Serine/threonine-protein kinase akt-1 antibody, AKT1 antibody, Akt1 antibody, ACTB antibody, akt1.S antibody, akt1 antibody, KT1 antibody, akt-1 antibody
背景
The PKB (RAC/akt) protein kinases are a family of second messenger-regulated serine/threonine kinases. Three mammalian isoforms (alpha, beta, gamma) have been identified so far, the alpha-isoform being the cellular homologue of the v-akt oncogene. Stimulation of cells with growth factors leads to activation of PKB by a phosphoinositide-3-kinase dependent signal transduction pathway.Synonyms: Akt-1, C-AKT, Protein kinase B, RAC-PK-alpha, RAC-alpha serine/threonine-protein kinase
分子量
60 kDa
基因ID
207
UniProt
P31749
途径
PI3K-Akt Signaling , RTK signaling , TCR Signaling , AMPK Signaling , Interferon-gamma Pathway , TLR signaling , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Response to Water Deprivation , Regulation of Actin Filament Polymerization , Carbohydrate Homeostasis , Glycosaminoglycan Metabolic Process , Cellular Glucan Metabolic Process , Regulation of Muscle Cell Differentiation , Cell-Cell Junction Organization , Regulation of Cell Size , Skeletal Muscle Fiber Development , Regulation of Carbohydrate Metabolic Process , Hepatitis C , Protein targeting to Nucleus , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Negative Regulation of intrinsic apoptotic Signaling , Thromboxane A2 Receptor Signaling , Signaling of Hepatocyte Growth Factor Receptor , Positive Regulation of fat Cell Differentiation , VEGFR1 Specific Signals , VEGF Signaling , Warburg Effect
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