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Insulin Receptor 抗体 (pTyr1322)

This anti-Insulin Receptor antibody is a 小鼠 单克隆 antibody detecting Insulin Receptor in WB 和 EIA. Suitable for 人, 小鼠 和 犬.
产品编号 ABIN126819
发货至: 中国

Quick Overview for Insulin Receptor 抗体 (pTyr1322) (ABIN126819)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 小鼠, 犬

宿主

  • 165
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  • 2
  • 1
小鼠

克隆类型

  • 151
  • 47
单克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

21G12
  • 抗原表位

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    pTyr1322

    特异性

    This antibody specifically recognizes Insulin receptor phosphorylated at Tyrosine 1322.

    产品特性

    Synonyms: Insulin Receptor

    纯化方法

    Size exclusion chromatography

    组件

    incl. positive Control

    免疫原

    Synthetic phosphopeptide conjugated to KLH.

    亚型

    IgG1
  • 应用备注

    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive Control: Cell lysate from pervanadate-treated HEK-293 cells. ELISA: 0.1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL H2O (15 min, RT).

    缓冲液

    1 mL2 x PBS containing 0.09 % Sodium Azide, PEG and Sucrose

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    Insulin Receptor (INSR)

    别名

    CD220 / INSR

    背景

    The insulin receptor (InsR) is a heterodimeric receptor tyrosine kinase with an extracellular alpha-chain, a transmembrane domain and an intracellular beta-chain. The insulin receptor is activated upon binding of the peptide hormone insulin, leading to autophosphorylation of tyrosine residues 1146, 1150, and 1151 in the activation loop of the beta-chain. Additional phosphorylation sites such as tyrosine residues 960, 1316, and 1322 regulate the assembly of signal transduction complexes.Synonyms: Insulin Receptor

    基因ID

    3643

    UniProt

    P06213

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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