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MAPK7 抗体 (N-Term)

The 小鼠 单克隆 anti-MAPK7 antibody is suitable to detect MAPK7 in samples from 人, 小鼠, 大鼠 和 犬. It has been validated for WB.
产品编号 ABIN126797
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for MAPK7 抗体 (N-Term) (ABIN126797)

抗原

See all MAPK7 抗体
MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

适用

  • 104
  • 73
  • 67
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
人, 小鼠, 大鼠, 犬

宿主

  • 135
  • 3
  • 2
  • 1
小鼠

克隆类型

  • 117
  • 24
单克隆

标记

  • 45
  • 11
  • 7
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 1
  • 1
  • 1
This MAPK7 antibody is un-conjugated

应用范围

  • 80
  • 54
  • 53
  • 37
  • 28
  • 23
  • 21
  • 20
  • 16
  • 15
  • 13
  • 1
  • 1
Western Blotting (WB)

克隆位点

12F2
  • 抗原表位

    • 16
    • 16
    • 15
    • 15
    • 15
    • 15
    • 10
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody recognizes MAP kinase 7 (erk5) at 92 kDa in Western-blot applications.

    产品特性

    Synonyms: Mitogen-activated protein kinase 7, Extracellular signal-regulated kinase 5, ERK4, Big MAPkinase 1, MAPK7

    纯化方法

    Size Exclusion Chromatography

    组件

    incl. positive Control

    免疫原

    Peptide conjugated to hemocyanin. AA Sequence: N-Terminus

    亚型

    IgG1
  • 应用备注

    Western Blot: 0.5 μg/mL for HRPO/ECL detection. Recommended blocking buffer: Casein/Tween 20 based blocking and blot incubationbuffer. Positive control: Cell lysate from untreated SKOV-3 cells.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with 1 mL H2O (15 min, RT).

    缓冲液

    1 mLPBS containing 0.09 % Sodium Azide, PEG and Sucrose

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C/-80 °C

    储存方法

    Store lyophilized (preferably in a desiccator) at -20 °C and reconstituted (aliquote andfreeze in liquid nitrogen) at -80 °C. Avoid repeated freezing and thawing. Thaw aliquots at 37 °C. Thawed aliquots may be stored at 4 °C up to 3 months.
    Shelf life: one year from despatch.

    有效期

    12 months
  • 抗原

    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

    别名

    MAPK7 / ERK5

    背景

    Erk5 (also known as MAPK7 or big mitogen activated kinase 1, BMK1) belongs to the Ser/Thr protein kinase family. It contains a T E Y motif in the activation loop similar to Erk1/2. Extracellular signals, including receptor tyrosine kinases and G-protein-coupled receptors as well as osmotic and oxdative stress lead to Erk5 activation by MEK5. The Erk5 pathway plays an important role in cellular proliferation, differentiation and survival.Synonyms: Big MAP kinase 1, ERK4, Extracellular signal-regulated kinase 5, MAPK7, Mitogen-activated protein kinase 7

    基因ID

    5598

    UniProt

    Q13164

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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