LRP1 抗体
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北京 101111
Quick Overview for LRP1 抗体 (ABIN125951)
抗原
See all LRP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This monoclonal antibody 5A6 specifically reacts with the 85 kDa beta-chain of LRP/alpha2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall. The antibody can also be used for the characterization of a subset of myelomonocytic subtypes of chronic and acute leukemia (CD 91). Cross-reacts with rabbit LDL receptor-related protein (LRP) or mouse LRP.
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Human LRP/alpha2MR.
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亚型
- IgG2b
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应用备注
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Immunofluorescence. Immunohistochemistry on Frozen Sections (Dilute 1/20). Flow Cytometry. Immunoblotting. Neutralizing effects of 5A6 have also been reported (cf. Basu et al. , 2001).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in 1 mL dist. water
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缓冲液
- Final solution contains 0.5 % BSA in PBS buffer, pH 7.4
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注意事项
- Do Not Add Sodium Azide
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注意事项
- Avoid repeated freezing and thawing. Dilute only prior to immediate use
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储存条件
- 4 °C/-20 °C
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储存方法
- Store vial at 2-8 °C prior to restoration. For extended storage add glycerol to 50% and then aliquot contents and freeze at -20 °C or below. Centrifuge product if not completely clear after standing at room temperature. This antibody is stable for one month at 2-8 °C as an undiluted liquid.
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- LRP1 (Low Density Lipoprotein Receptor-Related Protein 1 (LRP1))
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别名
- CD91 / LRP1
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背景
- Synonyms: A2MR, APOER, APR, Alpha-2-macroglobulin receptor, Apolipoprotein E receptor, Prolow-density lipoprotein receptor-related protein 1
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基因ID
- 4035
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NCBI登录号
- NP_002323
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UniProt
- Q07954
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途径
- Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
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