Leukotriene B4 Receptor/BLT 抗体
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北京 101111
Quick Overview for Leukotriene B4 Receptor/BLT 抗体 (ABIN122284)
抗原
See all Leukotriene B4 Receptor/BLT (LTB4R) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with Leukotriene B4 Receptor BLTR1/P2Y7 (Family: GPCR, Subfamily: Chemoattractant). BLAST analysis of the peptide immunogen showed no homology with other Human proteins.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Peptide Immunoaffinity Chromatography
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免疫原
- Synthetic peptide - KLH conjugated
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应用备注
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Immunohistochemistry on paraffin embedded sections: 5-10 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, pH 7.7, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- Leukotriene B4 Receptor/BLT (LTB4R) (Leukotriene B4 Receptor (LTB4R))
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别名
- LTB4R / BLTR
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背景
- BLT1 is a Chemoattractant Receptor that binds the potent chemoattractant leukotriene B4 (LTB4) which is involved in defense against infection. Leukotriene B4 also activates the transcription factor PPAR alpha, resulting in the activation of genes that terminate inflammatory processes. Although BLT1 shows homology to other P2Y receptors, it does not function as a purinoreceptor. Part of the coding regions of BLTR2 (LS57180) have been duplicated and are part of the 5' UTR noncoding regions of the clusters BLT1 (LS190955) and CIDE-B (LS54843) on chromosome 14. BLTR1 has been reported in blood, bone marrow, brain, heart, liver, and skeletal muscle. In addition, BLTR1 has been shown to be highly expressed in leukocytes and lymphoid tissues such as spleen, thymus, and lymph node. ESTs have been isolated from B-cell/lung/testis, breast, colon, eye, kidney, skin, spleen, testis, and tonsil libraries.Synonyms: BLT, BLT1, CMKRL1, Chemoattractant receptor-like 1, G-protein coupled receptor 16, GPR16, LTB4-R 1, Leukotriene B4 receptor 1, P2RY7, P2Y purinoceptor 7, P2Y7
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基因ID
- 1241
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UniProt
- Q15722
抗原
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