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- 抗原 See all CCR2 抗体
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CCR2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Reacts with CCR2 (family: GPCR, subfamily: Chemokine).
- 纯化方法
- Peptide immunogen affinity column
- 免疫原
- Synthetic peptide - KLH conjugated
- Top Product
- Discover our top product CCR2 Primary Antibody
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anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody
CCR2 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 3B6B1 unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人, 小鼠, 大鼠, 犬 IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 301-373) antibodyCCR2 适用: 人, 小鼠, 大鼠 ELISA, FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (N-Term) antibodyCCR2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Biotin)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (PE)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal PE
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (PerCP)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal PerCP
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (APC)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal APC
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Atto 488)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 488
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- 应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 3-30 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. - 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-80 °C
- 储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - 有效期
- 12 months
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- 抗原
- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
- 别名
- CD192 / CCR2 (CCR2 产品)
- 别名
- CC-CKR-2 antibody, CCR-2 antibody, CCR2A antibody, CCR2B antibody, CD192 antibody, CKR2 antibody, CKR2A antibody, CKR2B antibody, CMKBR2 antibody, MCP-1-R antibody, ACKR5 antibody, CKRX antibody, CRAM antibody, CRAM-A antibody, CRAM-B antibody, HCR antibody, Cc-ckr-2 antibody, Ccr2a antibody, Ccr2b antibody, Ckr2 antibody, Ckr2a antibody, Ckr2b antibody, Cmkbr2 antibody, mJe-r antibody, C-C motif chemokine receptor 2 antibody, C-C motif chemokine receptor like 2 antibody, chemokine (C-C motif) receptor 2 antibody, CCR2 antibody, CCRL2 antibody, Ccr2 antibody, LOC484790 antibody
- 背景
- CCR2, a Chemokine Receptor, is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis (Boring et al., 1998) and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration. Two isoforms are produced by alternative splicing. CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel. Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis (Ruth et al., 2001). ESTs have been isolated from liver/spleen and prostate libraries.Synonyms: C-C CKR-2, C-C chemokine receptor type 2, CC-CKR-2, CCR-2, CMKBR2, MCP1-Receptor, Monocyte chemoattractant protein 1 receptor
- 基因ID
- 729230
- UniProt
- P41597
- 途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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