CCR2 抗体
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北京 101111
Quick Overview for CCR2 抗体 (ABIN122022)
抗原
See all CCR2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with CCR2 (family: GPCR, subfamily: Chemokine).
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纯化方法
- Peptide immunogen affinity column
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免疫原
- Synthetic peptide - KLH conjugated
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anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody
CCR2 适用: 人 WB, FACS, ELISA 宿主: 小鼠 Monoclonal 3B6B1 unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 301-373) antibodyCCR2 适用: 人, 小鼠, 大鼠 FACS, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人, 小鼠, 大鼠, 犬 IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) (AA 19-32), (Extracellular), (N-Term) antibodyCCR2 适用: 小鼠 WB, FACS, IHC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Atto 488)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 488
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Atto 594)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 594
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (APC)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal APC
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Biotin)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibodyCCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Receptor 2 (CCR2) antibody (Atto 390)CCR2 适用: 人 WB, IHC 宿主: 兔 Polyclonal Atto 390
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应用备注
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Immunohistochemistry with formalin fixed paraffin embedded tissues: 3-30 μg/mL Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1x TBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: This product was originally produced by MBL International. -
限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.7, containing 0.01 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-80 °C
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储存方法
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -70 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- CCR2 (Chemokine (C-C Motif) Receptor 2 (CCR2))
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别名
- CD192 / CCR2
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背景
- CCR2, a Chemokine Receptor, is a regulator of monocyte/macrophage trafficking and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis (Boring et al., 1998) and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration. Two isoforms are produced by alternative splicing. CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel. Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis (Ruth et al., 2001). ESTs have been isolated from liver/spleen and prostate libraries.Synonyms: C-C CKR-2, C-C chemokine receptor type 2, CC-CKR-2, CCR-2, CMKBR2, MCP1-Receptor, Monocyte chemoattractant protein 1 receptor
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基因ID
- 729230
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UniProt
- P41597
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途径
- cAMP Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
抗原
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