CD40 Ligand 抗体
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北京 101111
Quick Overview for CD40 Ligand 抗体 (ABIN121931)
抗原
See all CD40 Ligand (CD40LG) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody is specific for the soluble form of human CD154, also designated CD40L (sCD40 Ligand), a member of the TNF receptor superfamily, comprising the full-length of the TNF homologous region of CD154.
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纯化方法
- Affinity chromatography
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免疫原
- Recombinant human soluble CD154
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应用备注
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ELISA (direct ELISA, 0.5 μg/mL). Western blot (0.1 - 0.2 μg).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 0.1 mL distilled water.
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline pH 7.4, containing no preservatives
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储存液
- Without preservative
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储存条件
- 4 °C/-20 °C
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储存方法
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Store lyophilized at 2 - 8 °C and reconstituted (undiluted) at -20 °C. Avoid repeated freezing and thawing. For long term storage the addition of 0.09 % sodium azide is recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: One year from despatch.Reconstitution: Restore with 0.1 ml distilled water.. -
有效期
- 12 months
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- CD40 Ligand (CD40LG)
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别名
- CD154 / CD40L
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背景
- CD154 is expressed predominantly on activated CD4+ T lymphocytes, and acts as a costimulatory molecule in B cell differentiation/proliferation, immunoglobulin switching and germinal centre formation, through interaction with the CD40 receptor on B cells, and cytokines secreted by activated T cells.Synonyms: CD40 ligand, CD40-L, CD40LG, GP39, T-cell antigen Gp39, TNF-related activation protein, TNFSF5, TRAP, Tumor necrosis factor ligand superfamily member 5
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基因ID
- 959
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UniProt
- P29965
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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