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MCL-1 抗体

MCL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN121915
发货至: 中国
  • 抗原 See all MCL-1 (MCL1) 抗体
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
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    克隆类型
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    多克隆
    标记
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    This MCL-1 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF)
    特异性
    This antibody recognizes an epitope within the central region (IN) of Myeloid cell leukaemia sequence 1 (MCL-1). SP2170P recognises both the MCL-1L (38 kDa) and MCL-1S (30 kDa) isoforms of MCL-1.
    纯化方法
    Ion Exchange Chromatography.
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    Discover our top product MCL1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
    别名
    MCL1 (MCL1 产品)
    背景
    MCL-1 is an anti-apoptotic member of the Bcl-2 family of proteins, first identified in differentiating ML-1 myeloid cells, and expressed in many different cell lines, tissues and a variety of tumours. The MCL-1 protein, localised to intracellular membranes and particularly mitochondrial membranes, has since been isolated in two distinct isoforms, known as MCL-1 long (MCL-1L) and MCL-1 short (MCL-1S). MCL-1S has been identified as a pro-apoptotic splice variant of MCL-1L, missing the transmembrane and BH1 and BH2 (Bcl-2 homology) domains. Interaction between these two antagonistic variants can act to regulate cell survival.Synonyms: BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein, EAT, Induced myeloid leukemia cell differentiation protein Mcl-1, mcl1/EAT, r004
    基因ID
    4170
    UniProt
    Q07820
    途径
    MAPK Pathway
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