IFNB1 抗体
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Quick Overview for IFNB1 抗体 (ABIN121882)
抗原
See all IFNB1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes Interferon beta (chIFN-beta). This antibody does not cross react with IFN gamma. This antiserum neutralizes chIFN-beta and can be used to discriminate IFN alpha and IFN beta bioactivities.
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产品特性
- Synonyms: IFN-beta, IFNB1, IFB, Fibroblast interferon
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纯化方法
- Affinity chromatography on protein G
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免疫原
- Recombinant chicken Interferon Beta
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应用备注
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Immunoprecipitation. Western Blot: This antibody detects a band of approximately 20 kDa. Funktional Assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS
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储存液
- Azide free
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储存条件
- -20 °C
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储存方法
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Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
有效期
- 12 months
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- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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别名
- IFNB / Interferon beta
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背景
- Reports suggest that chIFN exhibits properties similar to mammalian IFN type I (IFNI). Functional studies revealed the presence of two distantly related IFNI genes, designated as IFN alpha and IFN beta, found on chicken chromosome Z. The serological distinction between these two IFNs has been verified using neutralisation assays, and there is evidence that the antiviral activity of chIFN-beta is approximately tenfold less compared to chIFN-alpha. This would suggest that chIFNbeta might have a different physiological role, though chIFN-beta is expressed strongly in virus-infected cells.Synonyms: Fibroblast interferon, IFB, IFN-beta, IFNB1
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基因ID
- 554219
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UniProt
- Q90873
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途径
- JAK/STAT Signaling, TCR Signaling, TLR signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
抗原
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